Cyp2j7 cytochrome P450, family 2, subfamily j, polypeptide 7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cyp2j7provided by MGI
Official Full Name: cytochrome P450, family 2, subfamily j, polypeptide 7provided by MGI
Primary source: MGI:MGI:2449816
See related: Ensembl:ENSMUSG00000081362 AllianceGenome:MGI:2449816
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cyp2j7-ps
Summary: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 4 C5; 4 44.35 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	4	NC_000070.7 (96082684..96124896, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	4	NC_000070.6 (96195023..96236670, complement)

Chromosome 4 - NC_000070.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables arachidonate 11,12-epoxygenase activity	ISO Inferred from Sequence Orthology more info
enables arachidonate 14,15-epoxygenase activity	ISO Inferred from Sequence Orthology more info
enables arachidonate epoxygenase activity	ISO Inferred from Sequence Orthology more info
enables heme binding	IBA Inferred from Biological aspect of Ancestor more info
enables isomerase activity	ISO Inferred from Sequence Orthology more info
enables linoleic acid epoxygenase activity	ISO Inferred from Sequence Orthology more info
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in epoxygenase P450 pathway	ISO Inferred from Sequence Orthology more info
involved_in icosanoid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in linoleic acid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in organic acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in xenobiotic metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome P450, family 2, subfamily j, polypeptide 7

Names: cytochrome P450, 2j7; cytochrome P450, family 2, subfamily j, polypeptide 7, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001425033.1 → NP_001411962.1 cytochrome P450, family 2, subfamily j, polypeptide 7

Status: VALIDATED

Source sequence(s)

AL772395

UniProtKB/TrEMBL

A0A140T8U1

Related

ENSMUSP00000134331.2, ENSMUST00000162514.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000070.7 Reference GRCm39 C57BL/6J

Range

96082684..96124896 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NG_028253.4: Suppressed sequence

Description

NG_028253.4: This RefSeq was removed because it is now thought that this gene does encode a protein.
NM_001104926.1: Suppressed sequence

Description

NM_001104926.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.