Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

RecQ4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 53438, updated on 6-Jul-2014
Official Symbol
RecQ4provided by FlyBase
Primary source
FLYBASE:FBgn0040290
Locus tag
Dmel_CG7487
Gene type
protein coding
RNA name
RecQ4
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cg7487; CG7487; Dmel\CG7487; DmRECQ4; dRecQ4; RECQL4
See RecQ4 in Epigenomics, MapViewer
Location:
66B10-66B10
Exon count :
6
Annotation release Status Assembly Chr Location
Build 5.48 current Release 5 (GCF_000001215.2) 3L NT_037436.3 (8163740..8169078, complement)

Chromosome 3L - NT_037436.3Genomic Context describing neighboring genes Neighboring gene CG43886 gene product from transcript CG43886-RA Neighboring gene CG13675 gene product from transcript CG13675-RD Neighboring gene N-myristoyl transferase Neighboring gene methuselah-like 7

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP-dependent 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
DNA-dependent ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-dependent ATPase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
helicase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA duplex unwinding IDA
Inferred from Direct Assay
more info
PubMed 
DNA recombination IEA
Inferred from Electronic Annotation
more info
 
DNA repair ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
DNA replication ISS
Inferred from Sequence or Structural Similarity
more info
 
DNA rewinding IDA
Inferred from Direct Assay
more info
PubMed 
base-excision repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell division IMP
Inferred from Mutant Phenotype
more info
PubMed 
double-strand break repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
eggshell chorion gene amplification IMP
Inferred from Mutant Phenotype
more info
PubMed 
larval development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mitotic G2 DNA damage checkpoint IGI
Inferred from Genetic Interaction
more info
 
mitotic G2 DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
 
oogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of G2/M transition of mitotic cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with chromatin IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
CG7487 gene product from transcript CG7487-RA
Names
CG7487-PA
RecQ4
RecQ4-PA
NP_652607.1

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.3 

    Range
    8163740..8169078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_144350.2NP_652607.1  RecQ4 [Drosophila melanogaster]

    See proteins identical to NP_652607.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VSE6
    Related
    FBpp0076452, FBtr0076729
    Conserved Domains (3) summary
    COG0514
    Location:8641218
    Blast Score: 894
    RecQ; Superfamily II DNA helicase [DNA replication, recombination, and repair]
    cd00046
    Location:8941037
    Blast Score: 171
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd00079
    Location:10731216
    Blast Score: 291
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...