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L1CAM L1 cell adhesion molecule [ Bos taurus (cattle) ]

Gene ID: 516017, updated on 6-Jun-2024

Summary

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Official Symbol
L1CAMprovided by VGNC
Official Full Name
L1 cell adhesion moleculeprovided by VGNC
Primary source
VGNC:VGNC:30760
See related
BGD:BT18474; Ensembl:ENSBTAG00000013462
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See L1CAM in Genome Data Viewer
Location:
chromosome: X
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (37076263..37099784, complement)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene PDZ domain containing 4 Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene Rho GTPase activating protein 4 Neighboring gene arginine vasopressin receptor 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neural cell adhesion molecule L1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001192435.1 → NP_001179364.1  neural cell adhesion molecule L1 precursor

    See identical proteins and their annotated locations for NP_001179364.1

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000030
    UniProtKB/TrEMBL
    A0A3Q1LVV0, E1BBI3
    Related
    ENSBTAP00000017906.7, ENSBTAT00000017906.7
    Conserved Domains (9) summary
    cd05845
    Location:134 → 228
    Ig2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
    cd05867
    Location:347 → 422
    Ig4_L1-CAM_like; Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05876
    Location:260 → 330
    Ig3_L1-CAM; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    smart00409
    Location:524 → 608
    IG; Immunoglobulin
    smart00410
    Location:434 → 514
    IG_like; Immunoglobulin like
    cd00063
    Location:612 → 709
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:921 → 1003
    fn3; Fibronectin type III domain
    pfam13882
    Location:1144 → 1233
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:53 → 130
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    37076263..37099784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024987987.2 → XP_024843755.1  neural cell adhesion molecule L1 isoform X2

    UniProtKB/TrEMBL
    A0A3Q1LVV0
    Conserved Domains (9) summary
    cd05845
    Location:134 → 228
    Ig2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
    cd05867
    Location:347 → 422
    Ig4_L1-CAM_like; Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05876
    Location:260 → 330
    Ig3_L1-CAM; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    smart00409
    Location:524 → 608
    IG; Immunoglobulin
    smart00410
    Location:434 → 514
    IG_like; Immunoglobulin like
    cd00063
    Location:612 → 709
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:921 → 1003
    fn3; Fibronectin type III domain
    pfam13882
    Location:1144 → 1229
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:53 → 130
    Ig; Immunoglobulin domain

  2. XM_024987989.2 → XP_024843757.1  neural cell adhesion molecule L1 isoform X3

    UniProtKB/TrEMBL
    A0A3Q1LVV0, A0A3Q1NC56
    Related
    ENSBTAP00000068948.2, ENSBTAT00000068733.2
    Conserved Domains (9) summary
    cd05845
    Location:129 → 223
    Ig2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
    cd05867
    Location:342 → 417
    Ig4_L1-CAM_like; Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05876
    Location:255 → 325
    Ig3_L1-CAM; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    smart00409
    Location:519 → 603
    IG; Immunoglobulin
    smart00410
    Location:429 → 509
    IG_like; Immunoglobulin like
    cd00063
    Location:607 → 704
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:916 → 998
    fn3; Fibronectin type III domain
    pfam13882
    Location:1139 → 1224
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:48 → 125
    Ig; Immunoglobulin domain

  3. XM_015461516.3 → XP_015317002.2  neural cell adhesion molecule L1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q1MLS9
    Related
    ENSBTAP00000072651.1, ENSBTAT00000071285.2
    Conserved Domains (9) summary
    cd05845
    Location:265 → 359
    Ig2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM) and similar proteins
    cd05867
    Location:478 → 553
    Ig4_L1-CAM_like; Fourth immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05876
    Location:391 → 461
    Ig3_L1-CAM; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    smart00409
    Location:655 → 739
    IG; Immunoglobulin
    smart00410
    Location:565 → 645
    IG_like; Immunoglobulin like
    cd00063
    Location:743 → 840
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1052 → 1134
    fn3; Fibronectin type III domain
    pfam13882
    Location:1275 → 1360
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:184 → 261
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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