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spxA Spx family transcriptional regulator [ Streptococcus pyogenes str. Manfredo ]

Gene ID: 4964649, discontinued on 3-Feb-2015
  • All Gene records for this genome have been discontinued due to a change in scope for prokaryotic genomes in Gene. At the time this Gene record was discontinued, the RefSeq genome was re-annotated with the following features at this location:

Summary

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Gene symbol
spxA
Gene description
Spx family transcriptional regulator
Locus tag
SpyM50839
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Streptococcus pyogenes str. Manfredo (strain: Manfredo, serotype: M5)
Lineage
Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Also known as
yjbD
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009332.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Miscellaneous features

  • Loc: 844049-844381 HMMPfam hit to PF03960, ArsC family, score 6e-58 inference = protein motif:HMMPfam:PF03960

General protein information

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Names
Spx family transcriptional regulator
YP_001128398.1
  • the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_009332.1 Reference assembly

    Range
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_001128398.1 Spx family transcriptional regulator [Streptococcus pyogenes str. Manfredo]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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