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tnni1b troponin I type 1b (skeletal, slow) [ Danio rerio (zebrafish) ]

Gene ID: 494070, updated on 12-Sep-2024

Summary

Official Symbol
tnni1bprovided by ZNC
Official Full Name
troponin I type 1b (skeletal, slow)provided by ZNC
Primary source
ZFIN:ZDB-GENE-041212-37
See related
Ensembl:ENSDARG00000052708 AllianceGenome:ZFIN:ZDB-GENE-041212-37
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:103458
Summary
Acts upstream of or within heart development. Predicted to be part of troponin complex. Is expressed in cardiovascular system; lateral plate mesoderm; and musculature system. Orthologous to human TNNI1 (troponin I1, slow skeletal type). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See tnni1b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (54806931..54826061, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (54797122..54816248, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene plakophilin 1b Neighboring gene troponin T type 2b (cardiac) Neighboring gene neuron navigator 1b Neighboring gene cysteine and glycine-rich protein 1b Neighboring gene uncharacterized LOC103911280

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in cardiac muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within heart development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in heart valve development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in skeletal muscle contraction IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of troponin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of troponin complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
troponin I type 1b (skeletal, slow)
Names
TnnI-HC
troponin I, skeletal, slow b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008613.1NP_001008613.1  troponin I type 1b (skeletal, slow)

    See identical proteins and their annotated locations for NP_001008613.1

    Status: PROVISIONAL

    Source sequence(s)
    BC086814
    UniProtKB/TrEMBL
    Q5PR62
    Related
    ENSDARP00000124141.2, ENSDART00000149982.3
    Conserved Domains (1) summary
    pfam00992
    Location:15146
    Troponin; Troponin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    54806931..54826061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068221709.1XP_068077810.1  troponin I type 1b (skeletal, slow) isoform X1

    Related
    ENSDARP00000124278.2, ENSDART00000150079.3