Format

Send to:

Choose Destination

IQSEC2 IQ motif and Sec7 domain ArfGEF 2 [ Canis lupus familiaris (dog) ]

Gene ID: 491895, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
IQSEC2provided by VGNC
Official Full Name
IQ motif and Sec7 domain ArfGEF 2provided by VGNC
Primary source
VGNC:VGNC:42084
See related
Ensembl:ENSCAFG00845028820
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: X
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (45308027..45386860, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (36516736..36595958, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (45320205..45399024, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (44803229..44882038, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (45252874..45331684, complement)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102155331 Neighboring gene lysine demethylase 5C Neighboring gene 40S ribosomal protein SA-like Neighboring gene structural maintenance of chromosomes 1A

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
IQ motif and SEC7 domain-containing protein 2
Names
IQ motif and SEC7 domain-containing protein 2-like
IQ motif and Sec7 domain 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    45308027..45386860 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038450077.1 → XP_038306005.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0L6W5, A0A8C0SZP7
    Conserved Domains (4) summary
    pfam01369
    Location:753 → 941
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:961 → 1098
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1318 → 1425
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  2. XM_038450076.1 → XP_038306004.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0SWJ2, A0A8P0T1D5
    Conserved Domains (4) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1350 → 1457
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  3. XM_038450078.1 → XP_038306006.1  IQ motif and SEC7 domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:756 → 893
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1113 → 1220
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  4. XM_038450080.1 → XP_038306008.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:516 → 704
    Sec7; Sec7 domain
    pfam16453
    Location:724 → 861
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1081 → 1188
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  5. XM_038450079.1 → XP_038306007.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:522 → 710
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 867
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1087 → 1194
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  6. XM_038450081.1 → XP_038306009.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Z0S9, A0A8I3SBX0
    Related
    ENSCAFP00845040110.1, ENSCAFT00845051151.1
    Conserved Domains (2) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    44803229..44882038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038523525.1 → XP_038379453.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

    Conserved Domains (4) summary
    pfam01369
    Location:753 → 941
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:961 → 1098
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1318 → 1425
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  2. XM_038523524.1 → XP_038379452.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

    Conserved Domains (4) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1350 → 1457
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  3. XM_038523526.1 → XP_038379454.1  IQ motif and SEC7 domain-containing protein 2 isoform X3

    Conserved Domains (3) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:756 → 893
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1113 → 1220
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  4. XM_038523528.1 → XP_038379456.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

    Conserved Domains (3) summary
    pfam01369
    Location:516 → 704
    Sec7; Sec7 domain
    pfam16453
    Location:724 → 861
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1081 → 1188
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  5. XM_038523527.1 → XP_038379455.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    pfam01369
    Location:522 → 710
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 867
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1087 → 1194
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  6. XM_038523529.1 → XP_038379457.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

    Conserved Domains (2) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    45252874..45331684 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038652012.1 → XP_038507940.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

    Conserved Domains (4) summary
    pfam01369
    Location:753 → 941
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:961 → 1098
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1318 → 1425
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  2. XM_038652011.1 → XP_038507939.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

    Conserved Domains (4) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1350 → 1457
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  3. XM_038652013.1 → XP_038507941.1  IQ motif and SEC7 domain-containing protein 2 isoform X3

    Conserved Domains (3) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:756 → 893
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1113 → 1220
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  4. XM_038652015.1 → XP_038507943.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

    Conserved Domains (3) summary
    pfam01369
    Location:516 → 704
    Sec7; Sec7 domain
    pfam16453
    Location:724 → 861
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1081 → 1188
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  5. XM_038652014.1 → XP_038507942.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    pfam01369
    Location:522 → 710
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 867
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1087 → 1194
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  6. XM_038652016.1 → XP_038507944.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

    Conserved Domains (2) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    45320205..45399024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038587489.1 → XP_038443417.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0L6W5, A0A8C0SZP7
    Conserved Domains (4) summary
    pfam01369
    Location:753 → 941
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:961 → 1098
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1318 → 1425
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  2. XM_038587488.1 → XP_038443416.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0SWJ2, A0A8P0T1D5
    Conserved Domains (4) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1350 → 1457
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  3. XM_038587490.1 → XP_038443418.1  IQ motif and SEC7 domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:756 → 893
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1113 → 1220
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  4. XM_038587492.1 → XP_038443420.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:516 → 704
    Sec7; Sec7 domain
    pfam16453
    Location:724 → 861
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1081 → 1188
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  5. XM_038587491.1 → XP_038443419.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:522 → 710
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 867
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1087 → 1194
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  6. XM_038587493.1 → XP_038443421.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Z0S9, A0A8I3SBX0
    Conserved Domains (2) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    36516736..36595958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038464473.1 → XP_038320401.1  IQ motif and SEC7 domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0L6W5, A0A8C0SZP7
    Conserved Domains (4) summary
    pfam01369
    Location:753 → 941
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:961 → 1098
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1318 → 1425
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  2. XM_038464472.1 → XP_038320400.1  IQ motif and SEC7 domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0L6D3, A0A8C0SWJ2, A0A8P0T1D5
    Conserved Domains (4) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam08614
    Location:23 → 64
    ATG16; Autophagy protein 16 (ATG16)
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1350 → 1457
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  3. XM_549015.8 → XP_549015.4  IQ motif and SEC7 domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:548 → 736
    Sec7; Sec7 domain
    pfam16453
    Location:756 → 893
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1113 → 1220
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  4. XM_022416149.2 → XP_022271857.1  IQ motif and SEC7 domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:516 → 704
    Sec7; Sec7 domain
    pfam16453
    Location:724 → 861
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1081 → 1188
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  5. XM_014111705.3 → XP_013967180.1  IQ motif and SEC7 domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C0L6D3
    Conserved Domains (3) summary
    pfam01369
    Location:522 → 710
    Sec7; Sec7 domain
    pfam16453
    Location:730 → 867
    IQ_SEC7_PH; PH domain
    cl41729
    Location:1087 → 1194
    KLF1_2_4_N; N-terminal domain of Kruppel-like factor (KLF) 1, KLF2, KLF4, and similar proteins

  6. XM_038464475.1 → XP_038320403.1  IQ motif and SEC7 domain-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A8C0Z0S9, A0A8I3SBX0
    Conserved Domains (2) summary
    pfam01369
    Location:785 → 973
    Sec7; Sec7 domain
    pfam16453
    Location:993 → 1130
    IQ_SEC7_PH; PH domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials