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ISCA2 iron-sulfur cluster assembly 2 [ Canis lupus familiaris (dog) ]

Gene ID: 490783, updated on 17-Aug-2024

Summary

Official Symbol
ISCA2provided by VGNC
Official Full Name
iron-sulfur cluster assembly 2provided by VGNC
Primary source
VGNC:VGNC:42104
See related
Ensembl:ENSCAFG00845014307
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (47877829..47885208)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (47334798..47342174)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (47968246..47975623)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (47548997..47556348)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (47570242..47577621)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene synapse differentiation inducing 1 like Neighboring gene NPC intracellular cholesterol transporter 2 Neighboring gene latent transforming growth factor beta binding protein 2 Neighboring gene uncharacterized LOC119876505 Neighboring gene apoptosis resistant E3 ubiquitin protein ligase 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in iron-sulfur cluster assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein maturation by [4Fe-4S] cluster transfer IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
iron-sulfur cluster assembly 2 homolog, mitochondrial
Names
iron-sulfur cluster assembly 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    47877829..47885208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674186.1XP_038530114.1  iron-sulfur cluster assembly 2 homolog, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0P2Z5, A0A8C0QUL7, A0A8I3NJ84
    Related
    ENSCAFP00845020164.1, ENSCAFT00845025598.1
    Conserved Domains (1) summary
    cl00400
    Location:14153
    Fe-S_biosyn; Iron-sulphur cluster biosynthesis

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    47548997..47556348
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038483785.1XP_038339713.1  iron-sulfur cluster assembly 2 homolog, mitochondrial

    Conserved Domains (1) summary
    cl00400
    Location:14153
    Fe-S_biosyn; Iron-sulphur cluster biosynthesis

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    47570242..47577621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609362.1XP_038465290.1  iron-sulfur cluster assembly 2 homolog, mitochondrial

    Conserved Domains (1) summary
    cl00400
    Location:14153
    Fe-S_biosyn; Iron-sulphur cluster biosynthesis

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    47968246..47975623
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545266.1XP_038401194.1  iron-sulfur cluster assembly 2 homolog, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0P2Z5, A0A8C0QUL7, A0A8I3NJ84
    Conserved Domains (1) summary
    cl00400
    Location:14153
    Fe-S_biosyn; Iron-sulphur cluster biosynthesis

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    47334798..47342174
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_547905.7XP_547905.3  iron-sulfur cluster assembly 2 homolog, mitochondrial

    UniProtKB/TrEMBL
    A0A8C0P2Z5, A0A8C0QUL7, A0A8I3NJ84
    Conserved Domains (1) summary
    cl00400
    Location:14153
    Fe-S_biosyn; Iron-sulphur cluster biosynthesis