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SLC11A2 solute carrier family 11 member 2 [ Canis lupus familiaris (dog) ]

Gene ID: 486543, updated on 17-Aug-2024

Summary

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Official Symbol
SLC11A2provided by VGNC
Official Full Name
solute carrier family 11 member 2provided by VGNC
Primary source
VGNC:VGNC:46217
See related
Ensembl:ENSCAFG00845015776
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 27
Exon count:
23
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (3835730..3870717)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (42433184..42468214, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (42829654..42864682, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (3802428..3837405)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (3789782..3824709)

Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106557897 Neighboring gene cysteine and serine rich nuclear protein 2 Neighboring gene LETM1 domain containing 1 Neighboring gene HIG1 hypoxia inducible domain family member 1C Neighboring gene thiol methyltransferase 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadmium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in metal ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
natural resistance-associated macrophage protein 2
Names
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051831.1 Reference ROS_Cfam_1.0

    Range
    3835730..3870717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038438180.1 → XP_038294108.1  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N689, A0A8I3NMI2, A0A8I3RZ10, A0A8P0NWF7
    Related
    ENSCAFP00845022197.1, ENSCAFT00845028210.1
    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_038438182.1 → XP_038294110.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_038438181.1 → XP_038294109.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_038438184.1 → XP_038294112.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_038438183.1 → XP_038294111.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  6. XM_038438178.1 → XP_038294106.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  7. XM_038438179.1 → XP_038294107.1  natural resistance-associated macrophage protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z3Z9
    Related
    ENSCAFP00845022163.1, ENSCAFT00845028171.1
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049287.1 Alternate UMICH_Zoey_3.1

    Range
    3802428..3837405
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038512869.1 → XP_038368797.1  natural resistance-associated macrophage protein 2 isoform X3

    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_038512871.1 → XP_038368799.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_038512870.1 → XP_038368798.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_038512873.1 → XP_038368801.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_038512872.1 → XP_038368800.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  6. XM_038512867.1 → XP_038368795.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  7. XM_038512868.1 → XP_038368796.1  natural resistance-associated macrophage protein 2 isoform X2

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

    Range
    3789782..3824709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038640632.1 → XP_038496560.1  natural resistance-associated macrophage protein 2 isoform X3

    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_038640634.1 → XP_038496562.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_038640633.1 → XP_038496561.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_038640636.1 → XP_038496564.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_038640635.1 → XP_038496563.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  6. XM_038640630.1 → XP_038496558.1  natural resistance-associated macrophage protein 2 isoform X1

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  7. XM_038640631.1 → XP_038496559.1  natural resistance-associated macrophage protein 2 isoform X2

    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

    Range
    42829654..42864682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038577667.1 → XP_038433595.1  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N689, A0A8I3NMI2, A0A8I3RZ10, A0A8P0NWF7
    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_038577669.1 → XP_038433597.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_038577668.1 → XP_038433596.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_038577671.1 → XP_038433599.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_038577670.1 → XP_038433598.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  6. XM_038577665.1 → XP_038433593.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  7. XM_038577666.1 → XP_038433594.1  natural resistance-associated macrophage protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z3Z9
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    42433184..42468214 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_543669.6 → XP_543669.4  natural resistance-associated macrophage protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0N689, A0A8I3NMI2, A0A8I3RZ10, A0A8P0NWF7
    Conserved Domains (1) summary
    TIGR01197
    Location:96 → 495
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  2. XM_005636831.4 → XP_005636888.1  natural resistance-associated macrophage protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005636888.1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  3. XM_005636829.4 → XP_005636886.1  natural resistance-associated macrophage protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005636886.1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  4. XM_005636830.4 → XP_005636887.1  natural resistance-associated macrophage protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005636887.1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  5. XM_005636833.3 → XP_005636890.1  natural resistance-associated macrophage protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005636890.1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  6. XM_022410995.2 → XP_022266703.1  natural resistance-associated macrophage protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KPT0, A0A8C0Z3Z9, A0A8P0SD71
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters

  7. XM_038460114.1 → XP_038316042.1  natural resistance-associated macrophage protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0Z3Z9
    Conserved Domains (1) summary
    TIGR01197
    Location:68 → 467
    nramp; NRAMP (natural resistance-associated macrophage protein) metal ion transporters
Nucleotide Protein
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