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FOXA2 forkhead box A2 [ Canis lupus familiaris (dog) ]

Gene ID: 485742, updated on 17-Aug-2024

Summary

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Official Symbol
FOXA2provided by VGNC
Official Full Name
forkhead box A2provided by VGNC
Primary source
VGNC:VGNC:40944
See related
Ensembl:ENSCAFG00845027259
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
3
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 24 NC_051828.1 (1413104..1417432)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 24 NC_006606.4 (1034459..1038788)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 24 NC_049245.1 (1388439..1392767)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 24 NC_049284.1 (1010961..1015301)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 24 NC_049765.1 (1114770..1118263)

Chromosome 24 - NC_051828.1Genomic Context describing neighboring genes Neighboring gene surfeit locus protein 6-like Neighboring gene Y-box-binding protein 2-like Neighboring gene uncharacterized LOC102157329 Neighboring gene uncharacterized LOC111092157

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. FOXA2 depletion leads to mucus hypersecretion in canine airways with respiratory diseases. Choi W, et al. Cell Microbiol, 2019 Jan. PMID 30221439

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: hepatocyte nuclear factor 3-beta; hepatocyte nuclear factor 3-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051828.1 Reference ROS_Cfam_1.0

    Range
    1413104..1417432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038432953.1 → XP_038288881.1  hepatocyte nuclear factor 3-beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0TI73
    Conserved Domains (4) summary
    PRK07764
    Location:265 → 355
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam08430
    Location:17 → 158
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:382 → 454
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:157 → 258
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins

  2. XM_038432952.1 → XP_038288880.1  hepatocyte nuclear factor 3-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0LQB2, A0A8C0TI73, A0A8I3Q0G2
    Related
    ENSCAFP00845037686.1, ENSCAFT00845048031.1
    Conserved Domains (4) summary
    PRK07764
    Location:271 → 361
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam08430
    Location:23 → 164
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:388 → 460
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:163 → 264
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049284.1 Alternate UMICH_Zoey_3.1

    Range
    1010961..1015301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038508166.1 → XP_038364094.1  hepatocyte nuclear factor 3-beta isoform X2

  2. XM_038508165.1 → XP_038364093.1  hepatocyte nuclear factor 3-beta isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049765.1 Alternate UNSW_CanFamBas_1.0

    Range
    1114770..1118263
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038635656.1 → XP_038491584.1  LOW QUALITY PROTEIN: hepatocyte nuclear factor 3-beta isoform X1

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049245.1 Alternate UU_Cfam_GSD_1.0

    Range
    1388439..1392767
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038571421.1 → XP_038427349.1  hepatocyte nuclear factor 3-beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0TI73
    Conserved Domains (3) summary
    pfam08430
    Location:17 → 158
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:379 → 451
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:157 → 258
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins

  2. XM_038571420.1 → XP_038427348.1  hepatocyte nuclear factor 3-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0TI73, A0A8P0N7V3
    Conserved Domains (3) summary
    pfam08430
    Location:23 → 164
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:385 → 457
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:163 → 264
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006606.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1034459..1038788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458069.1 → XP_038313997.1  hepatocyte nuclear factor 3-beta isoform X2

    UniProtKB/TrEMBL
    A0A8C0TI73
    Conserved Domains (3) summary
    pfam08430
    Location:17 → 158
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:379 → 451
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:157 → 258
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins

  2. XM_542865.7 → XP_542865.3  hepatocyte nuclear factor 3-beta isoform X1

    UniProtKB/TrEMBL
    A0A8C0TI73, A0A8P0N7V3
    Conserved Domains (3) summary
    pfam08430
    Location:23 → 164
    Forkhead_N; Forkhead N-terminal region
    pfam09354
    Location:385 → 457
    HNF_C; HNF3 C-terminal domain
    cd20039
    Location:163 → 264
    FH_FOXA2; Forkhead (FH) domain found in Forkhead box protein A2 (FOXA2) and similar proteins
Nucleotide Protein
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