GDA guanine deaminase [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: GDAprovided by VGNC
Official Full Name: guanine deaminaseprovided by VGNC
Primary source: VGNC:VGNC:41154
See related: Ensembl:ENSCAFG00845000069
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (85957462..86037026, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (85972183..86051720, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (86182014..86261677, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (85718567..85798015, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (85423312..85502937, complement)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanine deaminase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in guanine catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: guanine deaminase

XP_038322314.1

EC 3.5.4.3

XP_038383009.1

EC 3.5.4.3

XP_038447313.1

EC 3.5.4.3

XP_038511125.1

EC 3.5.4.3

XP_541285.3

EC 3.5.4.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

85957462..86037026 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038655197.1 → XP_038511125.1 guanine deaminase

UniProtKB/TrEMBL

A0A8C0PUH1, A0A8I3M9U0, A0A8I3RQL8, A0A8P0TB79

Related

ENSCAFP00845000101.1, ENSCAFT00845000136.1

Conserved Domains (1) summary

cd01303
Location:13 → 444

GDEase; Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049261.1 Alternate UMICH_Zoey_3.1

Range

85718567..85798015 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038466386.1 → XP_038322314.1 guanine deaminase

Conserved Domains (1) summary

cd01303
Location:13 → 444

GDEase; Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049742.1 Alternate UNSW_CanFamBas_1.0

Range

85423312..85502937 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038591385.1 → XP_038447313.1 guanine deaminase

Conserved Domains (1) summary

cd01303
Location:13 → 444

GDEase; Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and ...

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049222.1 Alternate UU_Cfam_GSD_1.0

Range

86182014..86261677 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038527081.1 → XP_038383009.1 guanine deaminase

UniProtKB/TrEMBL

A0A8C0PUH1, A0A8I3M9U0, A0A8I3RQL8, A0A8P0TB79

Conserved Domains (1) summary

cd01303
Location:13 → 444

GDEase; Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

85972183..86051720 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_541285.7 → XP_541285.3 guanine deaminase

UniProtKB/TrEMBL

A0A8C0PUH1, A0A8I3M9U0, A0A8I3RQL8, A0A8P0TB79

Conserved Domains (1) summary

cd01303
Location:13 → 444

GDEase; Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and ...