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RECQL5 RecQ like helicase 5 [ Canis lupus familiaris (dog) ]

Gene ID: 483317, updated on 17-Aug-2024

Summary

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Official Symbol
RECQL5provided by VGNC
Official Full Name
RecQ like helicase 5provided by VGNC
Primary source
VGNC:VGNC:45459
See related
Ensembl:ENSCAFG00845024780
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See RECQL5 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
25
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (5573773..5611450)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (5582993..5620685)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (5784163..5821891)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (5613194..5650847)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (5723100..5760763)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 4 Neighboring gene SAP30 binding protein Neighboring gene myosin regulatory light polypeptide 9-like Neighboring gene small integral membrane protein 6 Neighboring gene myosin XVB Neighboring gene LLGL scribble cell polarity complex component 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ATP-dependent DNA helicase Q5; LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q5
Names
RecQ protein-like 5
XP_022278427.1
XP_022278428.1
XP_022278429.1
XP_022278430.1
XP_038340827.1
XP_038402511.1
XP_038402512.1
XP_038402513.1
XP_038402514.1
XP_038402515.1
XP_038402516.1
XP_038402517.1
XP_038466506.1
XP_038466507.1
XP_038466508.1
XP_038466509.1
XP_038466510.1
XP_038466512.1
XP_038466513.1
XP_038481432.1
XP_038481439.1
XP_038531633.1
XP_038531634.1
XP_038531636.1
XP_038531637.1
XP_038531638.1
XP_038531639.1
XP_038531640.1
XP_540436.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    5573773..5611450
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038675712.1 → XP_038531640.1  ATP-dependent DNA helicase Q5 isoform X7

    Conserved Domains (1) summary
    COG0514
    Location:11 → 406
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]

  2. XM_038675710.1 → XP_038531638.1  ATP-dependent DNA helicase Q5 isoform X5

    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 726
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  3. XM_038675705.1 → XP_038531633.1  ATP-dependent DNA helicase Q5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVF4
    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 832
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  4. XM_038675708.1 → XP_038531636.1  ATP-dependent DNA helicase Q5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PVF4
    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 741
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  5. XM_038675711.1 → XP_038531639.1  ATP-dependent DNA helicase Q5 isoform X6

    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 719
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  6. XM_038675706.1 → XP_038531634.1  ATP-dependent DNA helicase Q5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0PVF4, A0A8I3PIY6
    Related
    ENSCAFP00845034401.1, ENSCAFT00845043899.1
    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 825
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  7. XM_038675709.1 → XP_038531637.1  ATP-dependent DNA helicase Q5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PVF4, A0A8I3PXA0
    Related
    ENSCAFP00845034515.1, ENSCAFT00845044045.1
    Conserved Domains (2) summary
    COG0514
    Location:11 → 436
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:623 → 734
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

RNA

  1. XR_005431925.1 RNA Sequence

  2. XR_005431924.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    5613194..5650847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484899.1 → XP_038340827.1  LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q5 isoform X2

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    5723100..5760763
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038610585.1 → XP_038466513.1  ATP-dependent DNA helicase Q5 isoform X7

  2. XM_038610582.1 → XP_038466510.1  ATP-dependent DNA helicase Q5 isoform X5

  3. XM_038610580.1 → XP_038466508.1  ATP-dependent DNA helicase Q5 isoform X3

  4. XM_038610584.1 → XP_038466512.1  ATP-dependent DNA helicase Q5 isoform X6

  5. XM_038610578.1 → XP_038466506.1  ATP-dependent DNA helicase Q5 isoform X1

  6. XM_038610579.1 → XP_038466507.1  ATP-dependent DNA helicase Q5 isoform X2

  7. XM_038610581.1 → XP_038466509.1  ATP-dependent DNA helicase Q5 isoform X4

RNA

  1. XR_005398631.1 RNA Sequence

  2. XR_005398630.1 RNA Sequence

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    5784163..5821891
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038546589.1 → XP_038402517.1  ATP-dependent DNA helicase Q5 isoform X7

  2. XM_038546587.1 → XP_038402515.1  ATP-dependent DNA helicase Q5 isoform X5

  3. XM_038546585.1 → XP_038402513.1  ATP-dependent DNA helicase Q5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PVF4
    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 740
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  4. XM_038546588.1 → XP_038402516.1  ATP-dependent DNA helicase Q5 isoform X6

  5. XM_038546583.1 → XP_038402511.1  ATP-dependent DNA helicase Q5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVF4

  6. XM_038546584.1 → XP_038402512.1  ATP-dependent DNA helicase Q5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MBI7, A0A8C0PVF4, A0A8P0SAE7

  7. XM_038546586.1 → XP_038402514.1  ATP-dependent DNA helicase Q5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PVF4, A0A8P0P4I2
    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 733
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

RNA

  1. XR_005364203.1 RNA Sequence

  2. XR_005364202.1 RNA Sequence

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    5582993..5620685
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022422722.2 → XP_022278430.1  ATP-dependent DNA helicase Q5 isoform X7

    Conserved Domains (1) summary
    COG0514
    Location:11 → 405
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]

  2. XM_022422720.2 → XP_022278428.1  ATP-dependent DNA helicase Q5 isoform X5

    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 725
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  3. XM_038625504.1 → XP_038481432.1  ATP-dependent DNA helicase Q5 isoform X3

    UniProtKB/TrEMBL
    A0A8C0PVF4
    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 740
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  4. XM_022422721.2 → XP_022278429.1  ATP-dependent DNA helicase Q5 isoform X6

    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 718
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

  5. XM_022422719.2 → XP_022278427.1  ATP-dependent DNA helicase Q5 isoform X1

    UniProtKB/TrEMBL
    A0A8C0PVF4
    Conserved Domains (3) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 831
    RecQ5; RecQ helicase protein-like 5 (RecQ5)
    pfam08236
    Location:918 → 976
    SRI; SRI (Set2 Rpb1 interacting) domain

  6. XM_540436.7 → XP_540436.2  ATP-dependent DNA helicase Q5 isoform X2

    UniProtKB/TrEMBL
    A0A8C0MBI7, A0A8C0PVF4, A0A8P0SAE7
    Conserved Domains (6) summary
    smart00487
    Location:18 → 225
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:257 → 359
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam00270
    Location:27 → 197
    DEAD; DEAD/DEAH box helicase
    pfam06959
    Location:622 → 824
    RecQ5; RecQ helicase protein-like 5 (RecQ5)
    pfam08236
    Location:911 → 970
    SRI; SRI (Set2 Rpb1 interacting) domain
    pfam16124
    Location:364 → 431
    RecQ_Zn_bind; RecQ zinc-binding

  7. XM_038625511.1 → XP_038481439.1  ATP-dependent DNA helicase Q5 isoform X4

    UniProtKB/TrEMBL
    A0A8C0PVF4, A0A8P0P4I2
    Conserved Domains (2) summary
    COG0514
    Location:11 → 435
    RecQ; Superfamily II DNA helicase RecQ [Replication, recombination and repair]
    pfam06959
    Location:622 → 733
    RecQ5; RecQ helicase protein-like 5 (RecQ5)

RNA

  1. XR_002629718.2 RNA Sequence

  2. XR_002629716.2 RNA Sequence

Nucleotide Protein
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