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ATG2B autophagy related 2B [ Canis lupus familiaris (dog) ]

Gene ID: 480428, updated on 17-Aug-2024

Summary

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Official Symbol
ATG2Bprovided by VGNC
Official Full Name
autophagy related 2Bprovided by VGNC
Primary source
VGNC:VGNC:38222
See related
Ensembl:ENSCAFG00845003608
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
42
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 8 NC_051812.1 (65311353..65382558, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 8 NC_006590.4 (64555847..64626693, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 8 NC_049229.1 (65369420..65440283, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 8 NC_049268.1 (64984413..65055244, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 8 NC_049749.1 (65045745..65116666, complement)

Chromosome 8 - NC_051812.1Genomic Context describing neighboring genes Neighboring gene bradykinin receptor B2 Neighboring gene bradykinin receptor B1 Neighboring gene GSK3B interacting protein Neighboring gene adenylate kinase 7 Neighboring gene uncharacterized LOC119872922 Neighboring gene uncharacterized LOC111097154

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in piecemeal microautophagy of the nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in reticulophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
autophagy-related protein 2 homolog B; LOW QUALITY PROTEIN: autophagy-related protein 2 homolog B
Names
ATG2 autophagy related 2 homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051812.1 Reference ROS_Cfam_1.0

    Range
    65311353..65382558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674573.1 → XP_038530501.1  autophagy-related protein 2 homolog B isoform X2

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1997 → 2091
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

  2. XM_038674574.1 → XP_038530502.1  autophagy-related protein 2 homolog B isoform X3

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1997 → 2091
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

  3. XM_038674576.1 → XP_038530504.1  autophagy-related protein 2 homolog B isoform X4

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1978 → 2072
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

  4. XM_038674572.1 → XP_038530500.1  autophagy-related protein 2 homolog B isoform X1

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1998 → 2092
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

  5. XM_038674575.1 → XP_038530503.1  autophagy-related protein 2 homolog B isoform X6

    UniProtKB/TrEMBL
    A0A8C0KN88, A0A8I3MR37
    Related
    ENSCAFP00845005157.1, ENSCAFT00845006481.1
    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1979 → 2073
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

  6. XM_038674577.1 → XP_038530505.1  autophagy-related protein 2 homolog B isoform X5

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (2) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049268.1 Alternate UMICH_Zoey_3.1

    Range
    64984413..65055244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038484150.1 → XP_038340078.1  autophagy-related protein 2 homolog B isoform X2

  2. XM_038484151.1 → XP_038340079.1  autophagy-related protein 2 homolog B isoform X3

  3. XM_038484153.1 → XP_038340081.1  autophagy-related protein 2 homolog B isoform X4

  4. XM_038484149.1 → XP_038340077.1  autophagy-related protein 2 homolog B isoform X1

  5. XM_038484152.1 → XP_038340080.1  autophagy-related protein 2 homolog B isoform X6

  6. XM_038484154.1 → XP_038340082.1  autophagy-related protein 2 homolog B isoform X5

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049749.1 Alternate UNSW_CanFamBas_1.0

    Range
    65045745..65116666 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038609762.1 → XP_038465690.1  LOW QUALITY PROTEIN: autophagy-related protein 2 homolog B isoform X6

    Conserved Domains (3) summary
    COG5043
    Location:17 → 234
    MRS6; Vacuolar protein sorting-associated protein [Intracellular trafficking and secretion]
    pfam09333
    Location:1979 → 2073
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:16 → 105
    Chorein_N; N-terminal region of Chorein or VPS13

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049229.1 Alternate UU_Cfam_GSD_1.0

    Range
    65369420..65440283 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038545658.1 → XP_038401586.1  autophagy-related protein 2 homolog B isoform X2

    UniProtKB/TrEMBL
    A0A8C0KN88

  2. XM_038545659.1 → XP_038401587.1  autophagy-related protein 2 homolog B isoform X3

    UniProtKB/TrEMBL
    A0A8C0KN88

  3. XM_038545661.1 → XP_038401589.1  autophagy-related protein 2 homolog B isoform X4

    UniProtKB/TrEMBL
    A0A8C0KN88

  4. XM_038545657.1 → XP_038401585.1  autophagy-related protein 2 homolog B isoform X1

    UniProtKB/TrEMBL
    A0A8C0KN88

  5. XM_038545660.1 → XP_038401588.1  autophagy-related protein 2 homolog B isoform X6

    UniProtKB/TrEMBL
    A0A8C0KN88, A0A8C0MWZ1, A0A8P0SLX5

  6. XM_038545662.1 → XP_038401590.1  autophagy-related protein 2 homolog B isoform X5

    UniProtKB/TrEMBL
    A0A8C0KN88

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006590.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    64555847..64626693 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014116145.3 → XP_013971620.1  autophagy-related protein 2 homolog B isoform X2

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    pfam09333
    Location:1997 → 2091
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:11 → 105
    Chorein_N; N-terminal region of Chorein or VPS13
    pfam13329
    Location:1238 → 1358
    ATG2_CAD; Autophagy-related protein 2 CAD motif

  2. XM_022422358.2 → XP_022278066.1  autophagy-related protein 2 homolog B isoform X3

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    pfam09333
    Location:1997 → 2091
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:11 → 106
    Chorein_N; N-terminal region of Chorein or VPS13
    cl25572
    Location:17 → 234
    VPS13; Vacuolar sorting-associated protein 13, N-terminal

  3. XM_022422359.2 → XP_022278067.1  autophagy-related protein 2 homolog B isoform X4

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    pfam09333
    Location:1978 → 2072
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:11 → 106
    Chorein_N; N-terminal region of Chorein or VPS13
    cl25572
    Location:17 → 234
    VPS13; Vacuolar sorting-associated protein 13, N-terminal

  4. XM_014116144.3 → XP_013971619.1  autophagy-related protein 2 homolog B isoform X1

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (3) summary
    pfam09333
    Location:1998 → 2092
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:11 → 105
    Chorein_N; N-terminal region of Chorein or VPS13
    pfam13329
    Location:1239 → 1359
    ATG2_CAD; Autophagy-related protein 2 CAD motif

  5. XM_537549.6 → XP_537549.3  autophagy-related protein 2 homolog B isoform X6

    UniProtKB/TrEMBL
    A0A8C0KN88, A0A8C0MWZ1, A0A8P0SLX5
    Conserved Domains (3) summary
    pfam09333
    Location:1979 → 2073
    ATG_C; Autophagy-related protein C terminal domain
    pfam12624
    Location:11 → 105
    Chorein_N; N-terminal region of Chorein or VPS13
    pfam13329
    Location:1239 → 1359
    ATG2_CAD; Autophagy-related protein 2 CAD motif

  6. XM_014116146.3 → XP_013971621.1  autophagy-related protein 2 homolog B isoform X5

    UniProtKB/TrEMBL
    A0A8C0KN88
    Conserved Domains (2) summary
    pfam12624
    Location:11 → 105
    Chorein_N; N-terminal region of Chorein or VPS13
    pfam13329
    Location:1239 → 1359
    ATG2_CAD; Autophagy-related protein 2 CAD motif
Nucleotide Protein
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