CCR4 C-C motif chemokine receptor 4 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CCR4provided by VGNC
Official Full Name: C-C motif chemokine receptor 4provided by VGNC
Primary source: VGNC:VGNC:11365
Locus tag: CK820_G0009011
See related: Ensembl:ENSPTRG00000014725
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	2	NC_086015.1 (36970585..36976143)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	3	NC_072401.1 (36970235..36975808)

Chromosome 2 - NC_086015.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D3S4501 (e-PCR)
- UniSTS:474433

CCR4_517 (e-PCR)
- UniSTS:277064

RH91673 (e-PCR)
- UniSTS:87663

NoName (e-PCR)
- UniSTS:482160

SHGC-76800 (e-PCR)
- UniSTS:72360

G29868 (e-PCR)
- UniSTS:74164

PMC135988P7 (e-PCR)
- UniSTS:270793

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables C-C chemokine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables C-C chemokine receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in calcium-mediated signaling	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-C chemokine receptor type 4

Names: chemokine (C-C motif) receptor 4

XP_001168244.1

EC 3.1.13.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

36970585..36976143

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001168244.7 → XP_001168244.1 C-C chemokine receptor type 4

See identical proteins and their annotated locations for XP_001168244.1

UniProtKB/TrEMBL

A0A2J8NPV0, A0A2L2P6K8, A0A6D2XBA8, H2QM91

Related

ENSPTRP00000025398.4

Conserved Domains (1) summary

cd14984
Location:40 → 315

7tmA_Chemokine_R; classical and atypical chemokine receptors, member of the class A family of seven-transmembrane G protein-coupled receptors