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KDM6B lysine demethylase 6B [ Pan troglodytes (chimpanzee) ]

Gene ID: 468438, updated on 3-Apr-2024

Summary

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Official Symbol
KDM6Bprovided by VGNC
Official Full Name
lysine demethylase 6Bprovided by VGNC
Primary source
VGNC:VGNC:9345
Locus tag
CK820_G0036770
See related
Ensembl:ENSPTRG00000008710
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See KDM6B in Genome Data Viewer
Location:
chromosome: 17
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 19 NC_072417.2 (18348782..18370613)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 17 NC_072415.1 (16588302..16610105)

Chromosome 19 - NC_072417.2Genomic Context describing neighboring genes Neighboring gene ephrin B3 Neighboring gene dynein axonemal heavy chain 2 Neighboring gene large ribosomal subunit protein eL29-like Neighboring gene transmembrane protein 88 Neighboring gene N-alpha-acetyltransferase 38, NatC auxiliary subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K27me2/H3K27me3 demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MLL3/4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
lysine-specific demethylase 6B
Names
lysine (K)-specific demethylase 6B
XP_003315411.1
XP_009430032.1
XP_009430033.1
XP_009430037.1
XP_054526816.1
XP_054526817.1
XP_054526818.1
XP_063655619.1
XP_063655620.1
XP_063655621.1
XP_063655622.1
XP_063655623.1
XP_063655624.1
XP_063655625.1
XP_063655626.1
XP_063655627.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072417.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    18348782..18370613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054670841.2 → XP_054526816.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  2. XM_003315363.7 → XP_003315411.1  lysine-specific demethylase 6B isoform X1

    See identical proteins and their annotated locations for XP_003315411.1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4
    Conserved Domains (3) summary
    pfam02373
    Location:1374 → 1482
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:1340 → 1404
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cl26247
    Location:572 → 718
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  3. XM_063799554.1 → XP_063655624.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  4. XM_063799553.1 → XP_063655623.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  5. XM_063799549.1 → XP_063655619.1  lysine-specific demethylase 6B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4

  6. XM_063799550.1 → XP_063655620.1  lysine-specific demethylase 6B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4

  7. XM_063799552.1 → XP_063655622.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  8. XM_054670843.2 → XP_054526818.1  lysine-specific demethylase 6B isoform X3

  9. XM_009431758.5 → XP_009430033.1  lysine-specific demethylase 6B isoform X1

    See identical proteins and their annotated locations for XP_009430033.1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4
    Conserved Domains (3) summary
    pfam02373
    Location:1374 → 1482
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:1340 → 1404
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cl26247
    Location:572 → 718
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  10. XM_063799557.1 → XP_063655627.1  lysine-specific demethylase 6B isoform X4

  11. XM_063799555.1 → XP_063655625.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  12. XM_063799556.1 → XP_063655626.1  lysine-specific demethylase 6B isoform X3

  13. XM_009431762.5 → XP_009430037.1  lysine-specific demethylase 6B isoform X1

    See identical proteins and their annotated locations for XP_009430037.1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4
    Conserved Domains (3) summary
    pfam02373
    Location:1374 → 1482
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:1340 → 1404
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cl26247
    Location:572 → 718
    DNA_pol3_delta2; DNA polymerase III, delta subunit

  14. XM_063799551.1 → XP_063655621.1  lysine-specific demethylase 6B isoform X1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4

  15. XM_054670842.2 → XP_054526817.1  lysine-specific demethylase 6B isoform X2

    UniProtKB/TrEMBL
    A0A2J8KP91, A0A6D2XRB6, H2QC56

  16. XM_009431757.3 → XP_009430032.1  lysine-specific demethylase 6B isoform X1

    See identical proteins and their annotated locations for XP_009430032.1

    UniProtKB/TrEMBL
    A0A2J8KP79, A0A6D2WNK0, H2RGZ4
    Conserved Domains (3) summary
    pfam02373
    Location:1374 → 1482
    JmjC; JmjC domain, hydroxylase
    smart00558
    Location:1340 → 1404
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cl26247
    Location:572 → 718
    DNA_pol3_delta2; DNA polymerase III, delta subunit
Nucleotide Protein
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