NNT nicotinamide nucleotide transhydrogenase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: NNTprovided by VGNC
Official Full Name: nicotinamide nucleotide transhydrogenaseprovided by VGNC
Primary source: VGNC:VGNC:4102
Locus tag: CK820_G0044232
See related: Ensembl:ENSPTRG00000016851
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (69084942..69188069, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (69274447..69377613, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH18322 (e-PCR)
- UniSTS:36142

D5S2216E (e-PCR)
- UniSTS:154422

SHGC-111715 (e-PCR)
- UniSTS:168504

RH98326 (e-PCR)
- UniSTS:89150

SHGC-141773 (e-PCR)
- UniSTS:171076

RH75784 (e-PCR)
- UniSTS:87942

SHGC-100695 (e-PCR)
- UniSTS:183958

SHGC-105067 (e-PCR)
- UniSTS:169118

WI-10159 (e-PCR)
- UniSTS:40365

RH68867 (e-PCR)
- UniSTS:86961

D5S523E (e-PCR)
- UniSTS:473013

SHGC-106285 (e-PCR)
- UniSTS:183989

RH41165 (e-PCR)
- UniSTS:86208

RH25731 (e-PCR)
- UniSTS:84190

RH66587 (e-PCR)
- UniSTS:85991

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD(P)+ transhydrogenase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables NADP binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in NADPH regeneration	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NAD(P) transhydrogenase, mitochondrial

XP_009447470.1

EC 7.1.1.1

XP_009447471.1

EC 7.1.1.1

XP_009447472.1

EC 7.1.1.1

XP_009447473.1

EC 7.1.1.1

XP_016808823.1

EC 7.1.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

69084942..69188069 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009449197.5 → XP_009447472.1 NAD(P) transhydrogenase, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_009447472.1

UniProtKB/TrEMBL

A0A2J8JUR9, A0A2J8JUV1, A0A6D2YCT1, H2QQU7

Conserved Domains (2) summary

pfam02233
Location:622 → 1079

PNTB; NAD(P) transhydrogenase beta subunit

cl27049
Location:57 → 587

AlaDh_PNT_N; Alanine dehydrogenase/PNT, N-terminal domain
XM_009449198.5 → XP_009447473.1 NAD(P) transhydrogenase, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_009447473.1

UniProtKB/TrEMBL

A0A2J8JUR9, A0A2J8JUV1, A0A6D2YCT1, H2QQU7

Conserved Domains (2) summary

pfam02233
Location:622 → 1079

PNTB; NAD(P) transhydrogenase beta subunit

cl27049
Location:57 → 587

AlaDh_PNT_N; Alanine dehydrogenase/PNT, N-terminal domain
XM_009449195.5 → XP_009447470.1 NAD(P) transhydrogenase, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_009447470.1

UniProtKB/TrEMBL

A0A2J8JUR9, A0A2J8JUV1, A0A6D2YCT1, H2QQU7

Related

ENSPTRP00000028875.4

Conserved Domains (2) summary

pfam02233
Location:622 → 1079

PNTB; NAD(P) transhydrogenase beta subunit

cl27049
Location:57 → 587

AlaDh_PNT_N; Alanine dehydrogenase/PNT, N-terminal domain
XM_009449196.5 → XP_009447471.1 NAD(P) transhydrogenase, mitochondrial isoform X1

See identical proteins and their annotated locations for XP_009447471.1

UniProtKB/TrEMBL

A0A2J8JUR9, A0A2J8JUV1, A0A6D2YCT1, H2QQU7

Conserved Domains (2) summary

pfam02233
Location:622 → 1079

PNTB; NAD(P) transhydrogenase beta subunit

cl27049
Location:57 → 587

AlaDh_PNT_N; Alanine dehydrogenase/PNT, N-terminal domain
XM_016953334.4 → XP_016808823.1 NAD(P) transhydrogenase, mitochondrial isoform X2

UniProtKB/TrEMBL

A0A2J8JUR9

Conserved Domains (4) summary

PRK09424
Location:57 → 587

pntA; NAD(P) transhydrogenase subunit alpha; Provisional

cd05304
Location:57 → 432

Rubrum_tdh; Rubrum transdehydrogenase NAD-binding and catalytic domains

pfam02233
Location:622 → 959

PNTB; NAD(P) transhydrogenase beta subunit

pfam12769
Location:502 → 587

PNTB_4TM; 4TM region of pyridine nucleotide transhydrogenase, mitoch