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EIF6 eukaryotic translation initiation factor 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 458200, updated on 17-Aug-2024

Summary

Official Symbol
EIF6provided by VGNC
Official Full Name
eukaryotic translation initiation factor 6provided by VGNC
Primary source
VGNC:VGNC:6100
Locus tag
CK820_G0043082
See related
Ensembl:ENSPTRG00000013435
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
ITGB4BP
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 21 NC_072419.2 (41514793..41521604, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (41546530..41552469, complement)

Chromosome 21 - NC_072419.2Genomic Context describing neighboring genes Neighboring gene metallothionein-1L Neighboring gene MMP24 opposite strand Neighboring gene matrix metallopeptidase 24 Neighboring gene family with sequence similarity 83 member C Neighboring gene ubiquinol-cytochrome c reductase complex assembly factor 1 Neighboring gene growth differentiation factor 5

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ribosomal large subunit binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in assembly of large subunit precursor of preribosome IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cytosolic ribosome assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in maturation of 5.8S rRNA IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in maturation of LSU-rRNA IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in ribosomal subunit export from nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of preribosome, large subunit precursor IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
eukaryotic translation initiation factor 6
Names
integrin beta 4 binding protein
XP_001164435.1
XP_001164516.1
XP_009435368.1
XP_016793247.1
XP_063658917.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    41514793..41521604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001164516.7XP_001164516.1  eukaryotic translation initiation factor 6 isoform X1

    See identical proteins and their annotated locations for XP_001164516.1

    UniProtKB/TrEMBL
    A0A2J8JYL5, A0A6D2XB08, H2QK92
    Related
    ENSPTRP00000023044.3
    Conserved Domains (1) summary
    PTZ00136
    Location:1244
    PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional
  2. XM_016937758.2XP_016793247.1  eukaryotic translation initiation factor 6 isoform X2

    Conserved Domains (1) summary
    cl00241
    Location:107227
    IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...
  3. XM_009437093.4XP_009435368.1  eukaryotic translation initiation factor 6 isoform X3

    See identical proteins and their annotated locations for XP_009435368.1

    UniProtKB/TrEMBL
    A0A2I3RP92, A0A2J8JYN7, A0A6D2XFC4
    Related
    ENSPTRP00000066509.1
    Conserved Domains (1) summary
    cl00241
    Location:1225
    IF6; Ribosome anti-association factor IF6 binds the large ribosomal subunit and prevents the two subunits from associating during translation initiation. IF6 comprises a family of translation factors that includes both eukaryotic (eIF6) and archeal (aIF6) ...
  4. XM_063802847.1XP_063658917.1  eukaryotic translation initiation factor 6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8JYL5, A0A6D2XB08, H2QK92
  5. XM_001164435.8XP_001164435.1  eukaryotic translation initiation factor 6 isoform X1

    See identical proteins and their annotated locations for XP_001164435.1

    UniProtKB/TrEMBL
    A0A2J8JYL5, A0A6D2XB08, H2QK92
    Conserved Domains (1) summary
    PTZ00136
    Location:1244
    PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional