mmp9.1 matrix metallopeptidase 9 gene 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: mmp9.1provided by Xenbase
Official Full Name: matrix metallopeptidase 9 gene 1provided by Xenbase
Primary source: Xenbase:XB-GENE-876295
See related: Ensembl:ENSXETG00000008703
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: gelb; mmp9; MMP-9; clg4b; mandp2
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Genomic context

Location:: chromosome: 10

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	10	NC_030686.2 (19946664..19955013)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	10	NC_030686.1 (16277622..16285966, complement)

Chromosome 10 - NC_030686.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The MMP-9 gene was duplicated and differentiated into two genes, one was specialized in a common ancestor of X. laevis and X. tropicalis expressed in degenerating and remodeling organs in response to thyroid hormone during metamorphosis.
Title: One of the duplicated matrix metalloproteinase-9 genes is expressed in regressing tail during anuran metamorphosis.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info
enables metallopeptidase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within collagen catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular matrix	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: matrix metallopeptidase 9 gene 1

Names: matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

NP_001006843.1

EC 3.4.24.35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001006842.1 → NP_001006843.1 matrix metallopeptidase 9 gene 1 precursor

See identical proteins and their annotated locations for NP_001006843.1

Status: PROVISIONAL

Source sequence(s)

BC076927

UniProtKB/TrEMBL

A0A6I8PWC3, F6WFH6, Q6DF16

Related

ENSXETP00000019063.5, ENSXETT00000019063.5

Conserved Domains (4) summary

smart00059
Location:338 → 386

FN2; Fibronectin type 2 domain

cd00094
Location:480 → 667

HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...

pfam00413
Location:114 → 442

Peptidase_M10; Matrixin

pfam01471
Location:39 → 93

PG_binding_1; Putative peptidoglycan binding domain