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    raw [ Drosophila melanogaster ]

    Gene ID: 44851, updated on 10-May-2012
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    Summary

    Official Symbol
    rawprovided by Flybase
    Primary source
    FLYBASE:FBgn0003209
    Locus tag
    Dmel_CG12437
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12437; CG9321; cyr; Dmel\CG12437; ensh; l(2)06825; l(2)k03514
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    Genomic context

    Location :
    29E4-29E6; 2-19 cM
    Sequence :
    Chromosome: 2L; NT_033779.4 (8709880..8740660, complement)
    See raw in Epigenomics, MapViewer

    Chromosome 2L - NT_033779.4Genomic Context describing neighboring genes Neighboring gene CG9298 gene product from transcript CG9298-RA Neighboring gene Hepatocyte nuclear factor 4 Neighboring gene CG9314 gene product from transcript CG9314-RA Neighboring gene CG12438 gene product from transcript CG12438-RA Neighboring gene CG9463 gene product from transcript CG9463-RA

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Weyers JJ, et al. Dev Biol, 2011 May 15. PMID 21377458.
    2. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Zhang S, et al. Genetics, 2010 Apr. PMID 20100940.
    3. Raw mediates antagonism of AP-1 activity in Drosophila. Bates KL, et al. Genetics, 2008 Apr. PMID 18430930.
    4. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299.
    5. Positive selection near an inversion breakpoint on the neo-X chromosome of Drosophila americana. Evans AL, et al. Genetics, 2007 Nov. PMID 17660565.

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. In Drosophila, quenching of basal activator protein 1 (AP-1) transcription factor activity serves as a prerequisite to its tight spatial and temporal control by the JNK (Jun N-terminal kinase) signaling cascade.
      Title: Raw mediates antagonism of AP-1 activity in Drosophila.
    Submit: New GeneRIF Correction
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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:69328 BioGRID:59874 CG12194    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:65878 CG14671    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:62056 Ef1alpha48D    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:66904 Hsc70-4    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:61885 Jra    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:69328 BioGRID:70027 Pk17E    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:59150 Rad51D    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:63994 ago    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:59621 aop    BioGRID  PubMed Phenotypic Suppression 
    BioGRID:69328 BioGRID:64431 pix    BioGRID  PubMed Two-hybrid 
    BioGRID:69328 BioGRID:63569 zip    BioGRID  PubMed Phenotypic Suppression 
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    General gene information

    mobile_element

    • Loc: c8731490-8723170 mobile_element_type = transposon:Tirant{}328

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    Malpighian tubule morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    autophagic cell death IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    central nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    dorsal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    dorsal closure NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    dorsal closure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    dorsal closure, elongation of leading edge cells TAS
    Traceable Author Statement
    more info
    		 PubMed 
    ectodermal digestive tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    germ-band shortening IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    gonad development IMP
    Inferred from Mutant Phenotype
    more info
    		  
    hindgut morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    morphogenesis of an epithelium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    peripheral nervous system development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of JNK cascade NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    regulation of Malpighian tubule diameter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    regulation of cell shape IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    salivary gland cell autophagic cell death IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    salivary gland morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    CG12437 gene product from transcript CG12437-RB
    Names
    CG12437-PA
    CG12437-PB
    CG12437-PC
    cyrano
    ensheathment defects
    raw
    raw-PA
    raw-PB
    raw-PC
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    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.4

      Range
      8709880..8740660, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_080050.3 → NP_524789.2  raw, isoform B [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLI5
      Related
      FBpp0079347

    2. NM_001201804.1 → NP_001188733.1  raw, isoform C [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLI4

    3. NM_164836.2 → NP_723416.1  raw, isoform A [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VLI4
      Related
      FBpp0079348
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AE014134.5 AAF52705.2
    mRNA BT044207.1 ACH92272.1
    genomic AE014134.5 ADV36983.1
    genomic AE014134.5 AAF52706.2
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLI5.1 GenPept
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content