Tim17b2 Translocase inner membrane 17 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Tim17b2provided by FlyBase
Official Full Name: Translocase inner membrane 17provided by FlyBase
Primary source: FLYBASE:FBgn0020371
Locus tag: Dmel_CG15257
See related: AllianceGenome:FB:FBgn0020371
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:AT05822; BcDNA:AT13511; BG:DS01845.2; CG15257; Dmel\CG15257; dmTim17; Tim17
Summary: Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in positive regulation of protein processing and protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Predicted to be integral component of mitochondrial inner membrane. Is expressed in organism. Orthologous to human TIMM17A (translocase of inner mitochondrial membrane 17A) and TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (15484729..15485545)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (15484729..15485545)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to protein transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
contributes_to protein transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in protein insertion into mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TIM23 mitochondrial import inner membrane translocase complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
is_active_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info

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