CTLA4 cytotoxic T-lymphocyte associated protein 4 [Gallus gallus (chicken)] - Gene

Summary

Symbol: CTLA4provided by CGNC
Full Name: cytotoxic T-lymphocyte associated protein 4provided by CGNC
Primary source: CGNC:6579
See related: Ensembl:ENSGALG00010021983
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: CTLA-4
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	7	NC_052538.1 (13023423..13027636, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	7	NC_052579.1 (12947390..12951600, complement)

Chromosome 7 - NC_052538.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Process	Evidence Code	Pubs
involved_in B cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in T cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of regulatory T cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of T cell proliferation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cytotoxic T-lymphocyte protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001040091.2 → NP_001035180.1 cytotoxic T-lymphocyte protein 4 precursor

See identical proteins and their annotated locations for NP_001035180.1

Status: PROVISIONAL

Source sequence(s)

JAENSK010000236

UniProtKB/TrEMBL

Q1XDY5

Related

ENSGALP00010032215.1, ENSGALT00010053453.1

Conserved Domains (3) summary

smart00410
Location:87 → 135

IG_like; Immunoglobulin like

cl11960
Location:23 → 136

Ig; Immunoglobulin domain

cl22855
Location:138 → 184

TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052538.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

13023423..13027636 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052579.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

12947390..12951600 complement

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GenBank, FASTA, Sequence Viewer (Graphics)