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CG18493 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42319, updated on 18-Sep-2024

Summary

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Official Symbol
CG18493provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038701
Locus tag
Dmel_CG18493
See related
AllianceGenome:FB:FBgn0038701
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG18493
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. Is expressed in adult head and embryonic/larval midgut. Orthologous to human PRSS16 (serine protease 16). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
92A3-92A3; 3-66 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19390270..19392132)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15215992..15217854)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene INO80 complex subunit Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo. Olsen AL, et al. Glia, 2019 Oct. PMID 31267577, Free PMC Article
  2. Identification of the Telomere elongation Mutation in Drosophila. Reddy HM, et al. Cells, 2022 Nov 3. PMID 36359878, Free PMC Article
  3. GATAe-dependent and -independent expressions of genes in the differentiated endodermal midgut of Drosophila. Okumura T, et al. Gene Expr Patterns, 2007 Jan. PMID 16914392
  4. GATA factor genes in the Drosophila midgut embryo. Hernández de Madrid B, et al. PLoS One, 2018. PMID 29518114, Free PMC Article
  5. Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging. Jiao J, et al. Cell Rep, 2023 Jan 31. PMID 36640359, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables dipeptidyl-peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine hydrolase activity HDA PubMed 
enables serine-type exopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG18493-PA
NP_650803.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    19390270..19392132
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142546.2 → NP_650803.1  uncharacterized protein Dmel_CG18493 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650803.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SXK6, Q9VDX6
    Related
    FBpp0083170
    Conserved Domains (1) summary
    cl21494
    Location:61 → 471
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SXK6 Q8SXK6
Q9VDX6 Q9VDX6

Gene LinkOut

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