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SPRTN SprT-like N-terminal domain [ Gallus gallus (chicken) ]

Gene ID: 421530, updated on 5-Mar-2024

Summary

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Official Symbol
SPRTNprovided by CGNC
Official Full Name
SprT-like N-terminal domainprovided by CGNC
Primary source
CGNC:51502
See related
Ensembl:ENSGALG00010007970
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
DVC1; PRO4323; Spartan; C1orf124; DDDL1880; C3H1ORF124; dJ876B10.3
Orthologs
human mouse all
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Genomic context

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See SPRTN in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (39434483..39439252, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (39337645..39342414, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene translin associated factor X Neighboring gene egl-9 family hypoxia inducible factor 1 Neighboring gene exocyst complex component 8 Neighboring gene ras homolog family member U

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells. Nakazato A, et al. DNA Repair (Amst), 2018 Aug. PMID 29935364

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sprT-like domain-containing protein Spartan; DNA-dependent metalloprotease SPRTN
Names
DNA damage protein targeting VCP
DNA damage-targeting VCP (p97) adaptor
SprT-like domain at the N terminus
protein with SprT-like domain at the N terminus
zinc finger RAD18 domain-containing protein C1orf124

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    39434483..39439252 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_419571.8 → XP_419571.4  DNA-dependent metalloprotease SPRTN

    UniProtKB/TrEMBL
    E1BQ54
    Related
    ENSGALP00010010544.1, ENSGALT00010018995.1
    Conserved Domains (4) summary
    smart00734
    Location:518 → 540
    ZnF_Rad18; Rad18-like CCHC zinc finger
    smart00731
    Location:102 → 271
    SprT; SprT homologues
    COG5432
    Location:433 → 540
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    pfam05609
    Location:269 → 347
    LAP1C; Lamina-associated polypeptide 1C (LAP1C)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    39337645..39342414 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040667851.2 → XP_040523785.1  DNA-dependent metalloprotease SPRTN

    UniProtKB/TrEMBL
    E1BQ54
    Conserved Domains (4) summary
    smart00734
    Location:518 → 540
    ZnF_Rad18; Rad18-like CCHC zinc finger
    smart00731
    Location:102 → 271
    SprT; SprT homologues
    COG5432
    Location:433 → 540
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    pfam05609
    Location:269 → 347
    LAP1C; Lamina-associated polypeptide 1C (LAP1C)
Nucleotide Protein
Heading Accession and Version

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