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NDP NDP, norrin cystine knot growth factor [ Gallus gallus (chicken) ]

Gene ID: 418560, updated on 5-Mar-2024

Summary

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Symbol
NDPprovided by CGNC
Full Name
NDP, norrin cystine knot growth factorprovided by CGNC
Primary source
CGNC:12129
See related
Ensembl:ENSGALG00010011475
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See NDP in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (111261943..111281762)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (111347104..111366932)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene EF-hand domain containing 2 Neighboring gene uncharacterized LOC112531615 Neighboring gene monoamine oxidase B Neighboring gene monoamine oxidase A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-functional norrin is a ligand for the LGR4 receptor. Deng C, et al. J Cell Sci, 2013 May 1. PMID 23444378, Free PMC Article
  2. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Multi-functional norrin is a ligand for the LGR4 receptor.
    Title: Multi-functional norrin is a ligand for the LGR4 receptor.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
norrin
Names
Norrie disease (pseudoglioma)
Norrie disease protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278086.2 → NP_001265015.1  norrin precursor

    See identical proteins and their annotated locations for NP_001265015.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    JAENSK010000020
    UniProtKB/TrEMBL
    E1BWM4
    Conserved Domains (1) summary
    smart00041
    Location:43 → 129
    CT; C-terminal cystine knot-like domain (CTCK)

  2. NM_001278087.2 → NP_001265016.1  norrin precursor

    See identical proteins and their annotated locations for NP_001265016.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
    Source sequence(s)
    JAENSK010000020
    UniProtKB/TrEMBL
    E1BWM4
    Conserved Domains (1) summary
    smart00041
    Location:43 → 129
    CT; C-terminal cystine knot-like domain (CTCK)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    111261943..111281762
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015300447.4 → XP_015155933.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4
    Related
    ENSGALP00010015726.1, ENSGALT00010027475.1
    Conserved Domains (1) summary
    smart00041
    Location:43 → 129
    CT; C-terminal cystine knot-like domain (CTCK)

  2. XM_015300441.4 → XP_015155927.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4
    Conserved Domains (1) summary
    smart00041
    Location:43 → 129
    CT; C-terminal cystine knot-like domain (CTCK)

  3. XM_040698611.2 → XP_040554545.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4
    Conserved Domains (1) summary
    smart00041
    Location:43 → 129
    CT; C-terminal cystine knot-like domain (CTCK)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    111347104..111366932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046907918.1 → XP_046763874.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4

  2. XM_046907919.1 → XP_046763875.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4

  3. XM_046907917.1 → XP_046763873.1  norrin isoform X1

    UniProtKB/TrEMBL
    E1BWM4
Nucleotide Protein Strain
Heading Accession and Version

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