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CG6465 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41274, updated on 18-Sep-2024

Summary

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Official Symbol
CG6465provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0037818
Locus tag
Dmel_CG6465
See related
AllianceGenome:FB:FBgn0037818
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6465
Summary
Predicted to enable aminoacylase activity. Predicted to be involved in cellular amino acid metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including embryonic Malpighian tubule; embryonic/larval midgut primordium; foregut primordium; posterior endoderm; and proventriculus primordium. Orthologous to human ACY1 (aminoacylase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
86C4-86C4; 3-50 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10675560..10677251, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (6501282..6502973, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene mir-4944 stem loop Neighboring gene homothorax Neighboring gene antisense RNA:CR44018 Neighboring gene long non-coding RNA:CR44230 Neighboring gene Phytanoyl-CoA dioxygenase domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells. Willis DK, et al. J Insect Sci, 2010. PMID 20672983, Free PMC Article
  2. Drosophila as a diet discovery tool for treating amino acid disorders. Mele S, et al. Trends Endocrinol Metab, 2023 Feb. PMID 36567227
  3. siRNA screen identifies QPCT as a druggable target for Huntington's disease. Jimenez-Sanchez M, et al. Nat Chem Biol, 2015 May. PMID 25848931, Free PMC Article
  4. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
  5. Development of a Clickable Probe for Profiling of Protein Glutathionylation in the Central Cellular Metabolism of E. coli and Drosophila. Feng S, et al. Chem Biol, 2015 Nov 19. PMID 26526100

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aminoacylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aminoacylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6465-PA
NP_650004.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10675560..10677251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141747.3 → NP_650004.1  uncharacterized protein Dmel_CG6465 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650004.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9I7K3
    Related
    FBpp0081799
    Conserved Domains (2) summary
    cd05646
    Location:8 → 399
    M20_AcylaseI_like; M20 Aminoacylase-I like subfamily
    TIGR01880
    Location:1 → 401
    Ac-peptdase-euk; N-acyl-L-amino-acid amidohydrolase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I7K3 Q9I7K3

Gene LinkOut

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