U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Alp13 Alkaline phosphatase 13 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41236, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
Alp13provided by FlyBase
Official Full Name
Alkaline phosphatase 13provided by FlyBase
Primary source
FLYBASE:FBgn0037786
Locus tag
Dmel_CG5361
See related
AllianceGenome:FB:FBgn0037786
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5361; Dmel\CG5361
Summary
Predicted to enable alkaline phosphatase activity. Predicted to be involved in dephosphorylation. Is expressed in adult head; wing hinge primordium; and wing pouch. Human ortholog(s) of this gene implicated in adult hypophosphatasia; childhood hypophosphatasia; hypophosphatasia; and infantile hypophosphatasia. Orthologous to human ALPL (alkaline phosphatase, biomineralization associated). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
85F9-85F9; 3-49 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (10073821..10075373, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5899543..5901095, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene nervous fingers 2 Neighboring gene long non-coding RNA:CR45054 Neighboring gene mir-317 stem loop

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic architecture of olfactory behavior in Drosophila melanogaster: differences and similarities across development. Lavagnino NJ, et al. Behav Genet, 2013 Jul. PMID 23563598, Free PMC Article
  2. The complex I subunit NDUFA10 selectively rescues Drosophila pink1 mutants through a mechanism independent of mitophagy. Pogson JH, et al. PLoS Genet, 2014 Nov. PMID 25412178, Free PMC Article
  3. Modeling spinal muscular atrophy in Drosophila. Chang HC, et al. PLoS One, 2008 Sep 15. PMID 18791638, Free PMC Article
  4. The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster. Sitnik JL, et al. Genetics, 2016 Mar. PMID 26746709, Free PMC Article
  5. Computational identification of Drosophila microRNA genes. Lai EC, et al. Genome Biol, 2003. PMID 12844358, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alkaline phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alkaline phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
alkaline phosphatase 13
Names
Alp13-PB
CG5361-PB
NP_649978.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    10073821..10075373 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141721.2 → NP_649978.2  alkaline phosphatase 13 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649978.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4V6T1, Q9VH28
    Conserved Domains (1) summary
    cl23718
    Location:127 → 472
    ALP_like; alkaline phosphatases and sulfatases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VH28 Q9VH28

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous