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CG8132 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41121, updated on 10-May-2024

Summary

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Official Symbol
CG8132provided by FlyBase
Primary source
FLYBASE:FBgn0037687
Locus tag
Dmel_CG8132
See related
AllianceGenome:FB:FBgn0037687
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8132
Summary
Predicted to enable omega-amidase activity. Predicted to be involved in asparagine metabolic process; glutamine metabolic process; and oxaloacetate metabolic process. Is expressed in organism. Orthologous to human NIT2 (nitrilase family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG8132 in Genome Data Viewer
Location:
85D15-85D15; 3-48 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9401495..9402618)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5227217..5228340)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L34b Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene BBSome interacting protein 1 Neighboring gene uncharacterized protein Neighboring gene beta-Tubulin at 85D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An RNAi Screen for Genes Required for Growth of Drosophila Wing Tissue. Rotelli MD, et al. G3 (Bethesda), 2019 Oct 7. PMID 31387856, Free PMC Article
  2. A Genetic Screen Using the Drosophila melanogaster TRiP RNAi Collection To Identify Metabolic Enzymes Required for Eye Development. Pletcher RC, et al. G3 (Bethesda), 2019 Jul 9. PMID 31036678, Free PMC Article
  3. Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet. Çiçek IÖ, et al. Genetics, 2016 Mar. PMID 26801178, Free PMC Article
  4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
  5. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
Inferred from Electronic Annotation
more info
  
enables omega-amidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in asparagine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in oxaloacetate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8132-PA
NP_649888.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9401495..9402618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141631.3 → NP_649888.1  uncharacterized protein Dmel_CG8132 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649888.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHE4
    Related
    FBpp0081507
    Conserved Domains (1) summary
    cd07572
    Location:9 → 272
    nit; Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHE4 Q9VHE4

Gene LinkOut

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