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CG8032 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41026, updated on 10-May-2024

Summary

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Official Symbol
CG8032provided by FlyBase
Primary source
FLYBASE:FBgn0037606
Locus tag
Dmel_CG8032
See related
AllianceGenome:FB:FBgn0037606
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8032; PAOX
Summary
Predicted to enable polyamine oxidase activity. Is expressed in organism. Orthologous to several human genes including PAOX (polyamine oxidase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG8032 in Genome Data Viewer
Location:
85A5-85A5; 3-48 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8664115..8667772)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4489837..4493494)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Sys1 golgi trafficking protein Neighboring gene uncharacterized protein Neighboring gene belle Neighboring gene pink Neighboring gene transfer RNA:Tyrosine-GTA 1-6 Neighboring gene transfer RNA:Tyrosine-GTA 1-7 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The pink gene encodes the Drosophila orthologue of the human Hermansky-Pudlak syndrome 5 (HPS5) gene. Syrzycka M, et al. Genome, 2007 Jun. PMID 17632576
  2. Spatiotemporal patterning of polyamines in Drosophila development. Burnette M, et al. Amino Acids, 2015 Dec. PMID 26386564
  3. A gain-of-function screen to identify genes that reduce lifespan in the adult of Drosophila melanogaster. Nakayama M, et al. BMC Genet, 2014 Apr 16. PMID 24739137, Free PMC Article
  4. Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Greene JC, et al. Hum Mol Genet, 2005 Mar 15. PMID 15689351
  5. A Systematic Cell-Based Analysis of Localization of Predicted Drosophila Peroxisomal Proteins. Baron MN, et al. Traffic, 2016 May. PMID 26865094

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables polyamine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8032-PA
CG8032-PB
NP_001262380.1
NP_649811.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    8664115..8667772
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001275451.2 → NP_001262380.1  uncharacterized protein Dmel_CG8032, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001262380.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHN8
    Conserved Domains (2) summary
    pfam01593
    Location:49 → 556
    Amino_oxidase; Flavin containing amine oxidoreductase
    pfam13450
    Location:44 → 104
    NAD_binding_8; NAD(P)-binding Rossmann-like domain

  2. NM_141554.3 → NP_649811.1  uncharacterized protein Dmel_CG8032, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_649811.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VHN8
    Related
    FBpp0081369
    Conserved Domains (2) summary
    pfam01593
    Location:49 → 556
    Amino_oxidase; Flavin containing amine oxidoreductase
    pfam13450
    Location:44 → 104
    NAD_binding_8; NAD(P)-binding Rossmann-like domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VHN8 Q9VHN8

Gene LinkOut

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