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PDE6G phosphodiesterase 6G [ Canis lupus familiaris (dog) ]

Gene ID: 403911, updated on 17-Aug-2024

Summary

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Official Symbol
PDE6Gprovided by VGNC
Official Full Name
phosphodiesterase 6Gprovided by VGNC
Primary source
VGNC:VGNC:44361
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
PDEG
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (1120090..1122902)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (1128757..1131569)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (1350610..1353422)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (1144991..1147803)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (1271603..1274415)

Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 137 Neighboring gene oxidoreductase like domain containing 1 Neighboring gene tetraspanin 10 Neighboring gene NPL4 homolog, ubiquitin recognition factor Neighboring gene neuropeptide W

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of the cDNA and gene encoding the gamma-subunit of cGMP-phosphodiesterase in canine retinal rod photoreceptor cells. Wang W, et al. Gene, 1996 Nov 28. PMID 8973300
  2. Cloning of the cDNA encoding rod photoreceptor cGMP-phosphodiesterase alpha and gamma subunits from the retinal degenerate Labrador retriever dog. Kylmä T, et al. Res Vet Sci, 1997 May-Jun. PMID 9300552
  3. Elevation of cGMP with normal expression and activity of rod cGMP-PDE in photoreceptor degenerate labrador retrievers. Kommonen B, et al. Ophthalmic Res, 1996. PMID 8726673

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-nucleotide phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cGMP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in photoreceptor outer segment membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Names
GMP-PDE gamma
cyclic-GMP phosphodiesterase gamma subunit
NP_001003235.1
XP_038530894.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003235.1 → NP_001003235.1  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

    See identical proteins and their annotated locations for NP_001003235.1

    Status: PROVISIONAL

    Source sequence(s)
    U49359
    UniProtKB/Swiss-Prot
    P54827
    UniProtKB/TrEMBL
    A0A8C0K9N7
    Conserved Domains (1) summary
    pfam04868
    Location:5 → 87
    PDE6_gamma; Retinal cGMP phosphodiesterase, gamma subunit

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051813.1 Reference ROS_Cfam_1.0

    Range
    1120090..1122902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038674966.1 → XP_038530894.1  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma isoform X1

    UniProtKB/Swiss-Prot
    P54827
    UniProtKB/TrEMBL
    A0A8C0K9N7
    Conserved Domains (1) summary
    pfam04868
    Location:5 → 87
    PDE6_gamma; Retinal cGMP phosphodiesterase, gamma subunit

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049269.1 Alternate UMICH_Zoey_3.1

    Range
    1144991..1147803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

    Range
    1271603..1274415
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

    Range
    1350610..1353422
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    1128757..1131569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P54827.1 GenPept UniProtKB/Swiss-Prot:P54827

Gene LinkOut

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