cga glycoprotein hormones, alpha polypeptide [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cgaprovided by ZNC
Official Full Name: glycoprotein hormones, alpha polypeptideprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040715-2
See related: Ensembl:ENSDARG00000040479 AllianceGenome:ZFIN:ZDB-GENE-040715-2
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: GPHa; GTH-alpha; gsu-alpha
Summary: Predicted to enable follicle-stimulating hormone activity. Predicted to be involved in positive regulation of steroid biosynthetic process and thyroid hormone generation. Predicted to be located in extracellular region. Predicted to be part of follicle-stimulating hormone complex. Predicted to be active in extracellular space. Is expressed in several structures, including adenohypophyseal placode; female organism; hypophysis; kidney; and male organism. Orthologous to human CGA (glycoprotein hormones, alpha polypeptide). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 17

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (49439218..49443604, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (49356243..49360504, complement)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

gsualpha:EGFP transgenic zebrafish serve as a novel platform to perform screenings of endocrine-disrupting chemicals.
Title: Generation and characterization of gsuα:EGFP transgenic zebrafish for evaluating endocrine-disrupting effects.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables follicle-stimulating hormone activity	IBA Inferred from Biological aspect of Ancestor more info
enables hormone activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of steroid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in thyroid hormone generation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
part_of follicle-stimulating hormone complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glycoprotein hormones alpha chain

Names: gonadotropin alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.