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prox1.L prospero homeobox 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 399348, updated on 11-Apr-2024

Summary

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Official Symbol
prox1.L
Official Full Name
prospero homeobox 1 L homeolog
Primary source
Xenbase:XB-GENE-485331
Locus tag
XELAEV_18026219mg
See related
EnsemblRapid:ENSXLAG00005024151
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
prox1; xprox1; prospero
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Genomic context

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See prox1.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (12475399..12530217)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (11758491..11814145)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene angel homolog 2 L homeolog Neighboring gene ribosomal protein S6 kinase, 52kDa, polypeptide 1 L homeolog Neighboring gene uncharacterized LOC121393602 Neighboring gene SET and MYND domain containing 2 L homeolog Neighboring gene protein tyrosine phosphatase, non-receptor type 14 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pax-6 and Prox 1 expression during lens regeneration from Cynops iris and Xenopus cornea: evidence for a genetic program common to embryonic lens development. Mizuno N, et al. Differentiation, 1999 Nov. PMID 10631811

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
prospero homeobox 1 L homeolog
Names
Prox 1
prospero homeobox protein 1
prospero-related homeobox 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001090703.1 → NP_001084172.1  prospero homeobox 1 L homeolog

    See identical proteins and their annotated locations for NP_001084172.1

    Status: PROVISIONAL

    Source sequence(s)
    AB008773
    UniProtKB/TrEMBL
    A0A974CVM9, Q9DGF4
    Conserved Domains (2) summary
    pfam05044
    Location:582 → 733
    HPD; Homeo-prospero domain
    pfam09812
    Location:140 → 255
    MRP-L28; Mitochondrial ribosomal protein L28

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    12475399..12530217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562127.1 → XP_041418061.1  prospero homeobox 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KL65, A0A974CVM9
    Conserved Domains (1) summary
    pfam06428
    Location:221 → 268
    Sec2p; GDP/GTP exchange factor Sec2p

  2. XM_041562129.1 → XP_041418063.1  prospero homeobox 1 L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1KMV9, A0A974CVM9

  3. XM_041562128.1 → XP_041418062.1  prospero homeobox 1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1KL56, A0A974CVM9
    Related
    ENSXLAP00005071550.1, ENSXLAT00005073095.1
    Conserved Domains (1) summary
    pfam06428
    Location:221 → 268
    Sec2p; GDP/GTP exchange factor Sec2p

  4. XM_041562130.1 → XP_041418064.1  prospero homeobox 1 L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1KPA5, A0A974CVM9
    Related
    ENSXLAP00005071561.1, ENSXLAT00005073108.1
Nucleotide Protein Strain
Heading Accession and Version

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