prkci.L protein kinase C iota L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: prkci.L
Official Full Name: protein kinase C iota L homeolog
Primary source: Xenbase:XB-GENE-864810
Locus tag: XELAEV_18027593mg
See related: EnsemblRapid:ENSXLAG00005033675
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: apkc; prkci; prkcl; PKCiota; pkc-iota
Annotation information: Annotation category: partial on reference assembly
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 5L

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (119130731..119184377, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (108446284..108500118, complement)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The interaction and interdependence of Vangl2, VAMP1, aPKC and the stable microtubule cytoskeleton in the oocyte, shows that maternal Vangl2 and aPKC are required for specific oocyte asymmetries and vertebrate embryonic patterning.
Title: The roles of maternal Vangl2 and aPKC in Xenopus oocyte and embryo patterning.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables diacylglycerol-dependent serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phospholipid binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell-cell junction organization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: protein kinase C iota L homeolog

Names: atypical protein kinase c; protein kinase C subspecies lambda/iota

NP_001084068.1

EC 2.7.11.13

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090599.1 → NP_001084068.1 protein kinase C iota L homeolog

See identical proteins and their annotated locations for NP_001084068.1

Status: PROVISIONAL

Source sequence(s)

U12588

UniProtKB/TrEMBL

A0A974CXS9, Q91569

Related

ENSXLAP00005101721.1, ENSXLAT00005103708.1

Conserved Domains (4) summary

cd06404
Location:19 → 101

PB1_aPKC; PB1 domain is an essential modular domain of the atypical protein kinase C (aPKC) which in complex with Par6 and Par3 proteins is crucial for establishment of apical-basal polarity of animal cells. PB1 domain is a modular domain mediating specific ...

smart00220
Location:246 → 514

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd05618
Location:225 → 588

STKc_aPKC_iota; Catalytic domain of the Serine/Threonine Kinase, Atypical Protein Kinase C iota

pfam00130
Location:134 → 186

C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

119130731..119184377 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)