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rtn4.S reticulon 4 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398819, updated on 11-Apr-2024

Summary

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Official Symbol
rtn4.S
Official Full Name
reticulon 4 S homeolog
Primary source
Xenbase:XB-GENE-1012595
Locus tag
XELAEV_18028794mg
See related
EnsemblRapid:ENSXLAG00005023814
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
Nogo; rtn4; rtn4a; Nogo-A; rtn4-a; rtn4-b
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Genomic context

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See rtn4.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (25196595..25232436, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (25271500..25307625, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 75 S homeolog Neighboring gene spectrin, beta, non-erythrocytic 1 S homeolog Neighboring gene uncharacterized LOC121394166 Neighboring gene ribosomal protein S27a S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reticulon 4a/NogoA locates to regions of high membrane curvature and may have a role in nuclear envelope growth. Kiseleva E, et al. J Struct Biol, 2007 Nov. PMID 17889556, Free PMC Article
  2. Identification of two NOGO/RTN4 genes and analysis of Nogo-A expression in Xenopus laevis. Klinger M, et al. Mol Cell Neurosci, 2004 Feb. PMID 15019938
  3. Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress. Wang F, et al. Sci Rep, 2018 Feb 8. PMID 29422626, Free PMC Article
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Reticulon 4a/NogoA locates to regions of high membrane curvature and may have a role in nuclear envelope growth
    Title: Reticulon 4a/NogoA locates to regions of high membrane curvature and may have a role in nuclear envelope growth.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC68489

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within brain development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endoplasmic reticulum tubular network formation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within neuron differentiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
reticulon 4 S homeolog
Names
neurite outgrowth inhibition
reticulon 4 a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089769.1 → NP_001083238.1  reticulon 4 S homeolog

    See identical proteins and their annotated locations for NP_001083238.1

    Status: PROVISIONAL

    Source sequence(s)
    AY316196
    UniProtKB/TrEMBL
    Q6JRV0, Q6JRV1
    Related
    ENSXLAP00005070861.1, ENSXLAT00005072407.1
    Conserved Domains (1) summary
    pfam02453
    Location:868 → 1032
    Reticulon; Reticulon

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    25196595..25232436 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018264273.2 → XP_018119762.1  reticulon 4 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0VDF2, Q6JRV2
    Related
    ENSXLAP00005070943.1, ENSXLAT00005072489.1

  2. XM_018264272.2 → XP_018119761.1  reticulon 4 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8G1I6, A0A974CS84, Q5JBS0
    Related
    ENSXLAP00005071024.1, ENSXLAT00005072568.1

  3. XM_018264277.2 → XP_018119766.1  reticulon 4 S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J0VE92, Q6JRV3
    Related
    ENSXLAP00005070822.1, ENSXLAT00005072368.1

  4. XM_018264275.2 → XP_018119764.1  reticulon 4 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0VA54, Q6JRV4
    Related
    ENSXLAP00005070973.1, ENSXLAT00005072519.1

  5. XM_018264276.2 → XP_018119765.1  reticulon 4 S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0VD13, Q6JRV4
    Related
    ENSXLAP00005071089.1, ENSXLAT00005072636.1

  6. XM_018264278.1 → XP_018119767.1  reticulon 4 S homeolog isoform X6

    UniProtKB/TrEMBL
    Q6JRW3, Q6PB23
    Related
    ENSXLAP00005070596.1, ENSXLAT00005072136.1

  7. XM_018264280.1 → XP_018119769.1  reticulon 4 S homeolog isoform X7

    UniProtKB/TrEMBL
    Q6JRV6, Q6JRW4
Nucleotide Protein Strain
Heading Accession and Version

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