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ncam1.L neural cell adhesion molecule 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397762, updated on 11-Apr-2024

Summary

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Official Symbol
ncam1.L
Official Full Name
neural cell adhesion molecule 1 L homeolog
Primary source
Xenbase:XB-GENE-923178
Locus tag
XELAEV_18035552mg
See related
EnsemblRapid:ENSXLAG00005012163
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ncam; n-cam; ncam1; n-cam-1; ncam1-a; ncam1-b
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Genomic context

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See ncam1.L in Genome Data Viewer
Location:
chromosome: 7L
Exon count:
23
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (88701923..88849349, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (80084619..80235733, complement)

Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and kinase domain containing 1 L homeolog Neighboring gene tetratricopeptide repeat domain 12 L homeolog Neighboring gene uncharacterized LOC121395558 Neighboring gene uncharacterized LOC121395559 Neighboring gene uncharacterized LOC121395560 Neighboring gene placenta-expressed transcript 1 protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two neural-cell adhesion molecule (NCAM)-encoding genes in Xenopus laevis are expressed during development and in adult tissues. Tonissen KF, et al. Gene, 1993 May 30. PMID 7684721
  2. Molecular cloning of ssd-form neural cell adhesion molecules (N-CAMs) as the major form in Xenopus heart. Kudo M, et al. Biochem Biophys Res Commun, 1998 Apr 7. PMID 9535795
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within synapse organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neural cell adhesion molecule 1-B
Names
N-CAM-1-B
NCAM-1-B
cell adhesion molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087829.1 → NP_001081298.1  neural cell adhesion molecule 1-B precursor

    See identical proteins and their annotated locations for NP_001081298.1

    Status: PROVISIONAL

    Source sequence(s)
    M76710
    UniProtKB/Swiss-Prot
    P36335
    Related
    ENSXLAP00005035706.1, ENSXLAT00005036599.1
    Conserved Domains (7) summary
    cd05730
    Location:208 → 302
    Ig3_NCAM-1_like; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule NCAM-1 (NCAM)
    smart00408
    Location:412 → 480
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:219 → 299
    IG_like; Immunoglobulin like
    cd00063
    Location:492 → 589
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24 → 111
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:621 → 679
    fn3; Fibronectin type III domain
    cl11960
    Location:301 → 396
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    88701923..88849349 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018224336.2 → XP_018079825.1  neural cell adhesion molecule 1-B isoform X3

    UniProtKB/TrEMBL
    A0A8J0T922
    Related
    ENSXLAP00005035726.1, ENSXLAT00005036620.1

  2. XM_041568392.1 → XP_041424326.1  neural cell adhesion molecule 1-B isoform X1

    UniProtKB/TrEMBL
    A0A8J1L449
    Conserved Domains (6) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    smart00409
    Location:137 → 203
    IG; Immunoglobulin
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:518 → 615
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:335 → 339
    Ig; Ig strand B [structural motif]
    cl11960
    Location:317 → 422
    Ig; Immunoglobulin domain

  3. XM_041568393.1 → XP_041424327.1  neural cell adhesion molecule 1-B isoform X4

    UniProtKB/TrEMBL
    A0A8J1L453
    Conserved Domains (5) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:508 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:335 → 339
    Ig; Ig strand B [structural motif]
    cl11960
    Location:317 → 412
    Ig; Immunoglobulin domain

  4. XM_018224335.2 → XP_018079824.1  neural cell adhesion molecule 1-B isoform X2

    UniProtKB/TrEMBL
    A0A8J0T850

  5. XM_041568395.1 → XP_041424329.1  neural cell adhesion molecule 1-B isoform X7

    UniProtKB/TrEMBL
    A0A8J1L5V7
    Conserved Domains (6) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    smart00409
    Location:431 → 514
    IG; Immunoglobulin
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:518 → 615
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:335 → 339
    Ig; Ig strand B [structural motif]
    cl11960
    Location:317 → 422
    Ig; Immunoglobulin domain

  6. XM_018224338.2 → XP_018079827.1  neural cell adhesion molecule 1-B isoform X6

    UniProtKB/TrEMBL
    A0A1L8FLT9, A0A974HC70

  7. XM_018224337.2 → XP_018079826.1  neural cell adhesion molecule 1-B isoform X5

    UniProtKB/TrEMBL
    A0A8J0T5X5
    Related
    ENSXLAP00005035731.1, ENSXLAT00005036624.1

  8. XM_041568396.1 → XP_041424330.1  neural cell adhesion molecule 1-B isoform X9

    UniProtKB/TrEMBL
    A0A8J1L6W2
    Conserved Domains (6) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    smart00409
    Location:431 → 514
    IG; Immunoglobulin
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:518 → 615
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:335 → 339
    Ig; Ig strand B [structural motif]
    cl11960
    Location:317 → 422
    Ig; Immunoglobulin domain

  9. XM_018224339.2 → XP_018079828.1  neural cell adhesion molecule 1-B isoform X8

    UniProtKB/TrEMBL
    A0A8J0T856

  10. XM_041568397.1 → XP_041424331.1  neural cell adhesion molecule 1-B isoform X11

    UniProtKB/TrEMBL
    A0A8J1L455, O73634
    Conserved Domains (6) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    cd05869
    Location:317 → 412
    IgI_NCAM-1; Immunoglobulin (Ig)-like I-set domain of Neural Cell Adhesion Molecule 1 (NCAM-1)
    smart00409
    Location:137 → 203
    IG; Immunoglobulin
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:508 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:53 → 57
    Ig; Ig strand B [structural motif]

  11. XM_018224340.2 → XP_018079829.1  neural cell adhesion molecule 1-B isoform X10

    UniProtKB/TrEMBL
    A0A8J0T857, O73634

  12. XM_041568398.1 → XP_041424332.1  neural cell adhesion molecule 1-B isoform X12

    UniProtKB/TrEMBL
    A0A8J1L459, O73634
    Related
    ENSXLAP00005035723.1, ENSXLAT00005036616.1
    Conserved Domains (6) summary
    cd05730
    Location:224 → 318
    IgI_3_NCAM-1; Third immunoglobulin (Ig)-like domain of Neural Cell Adhesion Molecule 1 (NCAM-1); member of the I-set of IgSF domains
    cd05869
    Location:317 → 412
    IgI_NCAM-1; Immunoglobulin (Ig)-like I-set domain of Neural Cell Adhesion Molecule 1 (NCAM-1)
    smart00409
    Location:421 → 504
    IG; Immunoglobulin
    smart00410
    Location:42 → 127
    IG_like; Immunoglobulin like
    cd00063
    Location:508 → 605
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:53 → 57
    Ig; Ig strand B [structural motif]

  13. XM_018224341.2 → XP_018079830.1  neural cell adhesion molecule 1-B isoform X13

    UniProtKB/TrEMBL
    A0A8J0T927, O73634
    Related
    ENSXLAP00005035712.1, ENSXLAT00005036605.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P36335.1 GenPept UniProtKB/Swiss-Prot:P36335

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