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PVALB parvalbumin [ Gallus gallus (chicken) ]

Gene ID: 396459, updated on 17-Aug-2024

Summary

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Official Symbol
PVALBprovided by CGNC
Official Full Name
parvalbuminprovided by CGNC
Primary source
CGNC:49814
See related
Ensembl:ENSGALG00010014889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
pvalb1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (51647769..51661023)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (51942212..51955516)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene colony stimulating factor 2 receptor beta common subunit Neighboring gene cytokine receptor common subunit beta-like Neighboring gene neutrophil cytosolic factor 4 Neighboring gene intraflagellar transport 27 Neighboring gene calcium voltage-gated channel auxiliary subunit gamma 2 Neighboring gene eukaryotic translation initiation factor 3 subunit D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparison of the amino acid sequences of tissue-specific parvalbumins from chicken muscle and thymus and possible evolutionary significance. Brewer JM, et al. Biochem Biophys Res Commun, 1991 Nov 27. PMID 1958191
  2. Parvalbumin isoforms in chicken muscle and thymus. Amino acid sequence analysis of muscle parvalbumin by tandem mass spectrometry. Kuster T, et al. Biochemistry, 1991 Sep 10. PMID 1888741
  3. Avian thymic hormone and chicken (muscle) parvalbumin are distinct proteins: isolation of a muscle parvalbumin cDNA fragment by PCR. Palmisano WA, et al. Biochem Biophys Res Commun, 1991 Apr 15. PMID 1708248
  4. Immunohistochemical localization of parvalbumin calcium-binding protein in the heart tissues of various species. Vongvatcharanon S, et al. Acta Histochem, 2008. PMID 17706751
  5. Food allergy to chicken meat with IgE reactivity to muscle alpha-parvalbumin. Kuehn A, et al. Allergy, 2009 Oct. PMID 19772518

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show the cardiac myocytes had Parvalbumin in their cytoplasm and intensity of PV immunoreactivity may be correlated with the physical activity of the heart.
    Title: Immunohistochemical localization of parvalbumin calcium-binding protein in the heart tissues of various species.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
parvalbumin, muscle
Names
PARVALBUMIN protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159315.2 → NP_001152787.1  parvalbumin, muscle isoform a

    See identical proteins and their annotated locations for NP_001152787.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370
    Related
    ENSGALP00010020777.1, ENSGALT00010035827.1
    Conserved Domains (1) summary
    cd16254
    Location:9 → 109
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

  2. NM_001397892.1 → NP_001384821.1  parvalbumin, muscle isoform a

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370
    Conserved Domains (1) summary
    cd16254
    Location:9 → 109
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

  3. NM_001397893.1 → NP_001384822.1  parvalbumin, muscle isoform b

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000012
    UniProtKB/Swiss-Prot
    P80026
    Conserved Domains (1) summary
    cd16254
    Location:9 → 108
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    51647769..51661023
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046923253.1 → XP_046779209.1  parvalbumin, muscle isoform X1

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370

  2. XM_040670293.2 → XP_040526227.1  parvalbumin, muscle isoform X3

    UniProtKB/Swiss-Prot
    P80026
    Conserved Domains (1) summary
    cd16254
    Location:9 → 108
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

  3. XM_046923231.1 → XP_046779187.1  parvalbumin, muscle isoform X2

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    A0A1D5P544
    Related
    ENSGALP00010020775.1, ENSGALT00010035824.1

  4. XM_025146985.3 → XP_025002753.2  parvalbumin, muscle isoform X4

    UniProtKB/Swiss-Prot
    P80026
    Conserved Domains (1) summary
    cd16254
    Location:33 → 132
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

  5. XM_046923197.1 → XP_046779153.1  parvalbumin, muscle isoform X1

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370

  6. XM_046923278.1 → XP_046779234.1  parvalbumin, muscle isoform X3

    UniProtKB/Swiss-Prot
    P80026

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    51942212..51955516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046906939.1 → XP_046762895.1  parvalbumin, muscle isoform X1

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370

  2. XM_046906941.1 → XP_046762897.1  parvalbumin, muscle isoform X3

    UniProtKB/Swiss-Prot
    P80026

  3. XM_046906938.1 → XP_046762894.1  parvalbumin, muscle isoform X2

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    A0A1D5P544

  4. XM_046906942.1 → XP_046762898.1  parvalbumin, muscle isoform X4

    UniProtKB/Swiss-Prot
    P80026
    Conserved Domains (1) summary
    cd16254
    Location:33 → 132
    EFh_parvalbumin_alpha; EF-hand, calcium binding motif, found in alpha-parvalbumin

  5. XM_046906937.1 → XP_046762893.1  parvalbumin, muscle isoform X1

    UniProtKB/Swiss-Prot
    P80026
    UniProtKB/TrEMBL
    C1L370

  6. XM_046906940.1 → XP_046762896.1  parvalbumin, muscle isoform X3

    UniProtKB/Swiss-Prot
    P80026
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P80026.1 GenPept UniProtKB/Swiss-Prot:P80026

Gene LinkOut

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Research Materials