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Ermard ER membrane associated RNA degradation [ Mus musculus (house mouse) ]

Gene ID: 381062, updated on 17-Aug-2024

Summary

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Official Symbol
Ermardprovided by MGI
Official Full Name
ER membrane associated RNA degradationprovided by MGI
Primary source
MGI:MGI:1917317
See related
Ensembl:ENSMUSG00000036552 AllianceGenome:MGI:1917317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210404J11Rik; 2410011O22Rik
Summary
Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ERMARD (ER membrane associated RNA degradation). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 5.1), cerebellum adult (RPKM 4.3) and 28 other tissues See more
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Genomic context

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See Ermard in Genome Data Viewer
Location:
17 A2; 17 8.95 cM
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (15261825..15310307)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (15041551..15090045)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene dynein light chain Tctex-type 2A2 Neighboring gene STARR-seq mESC enhancer starr_41899 Neighboring gene ER membrane associated RNA degradation like 1 Neighboring gene dynein light chain Tctex-type 2A1 Neighboring gene predicted gene, 52298 Neighboring gene STARR-seq mESC enhancer starr_41900 Neighboring gene predicted gene, 53990 Neighboring gene predicted gene, 35343 Neighboring gene predicted gene, 41532 Neighboring gene predicted gene, 35203 Neighboring gene predicted gene, 35455 Neighboring gene STARR-seq mESC enhancer starr_41901 Neighboring gene predicted gene, 35502

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
  2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ER membrane associated RNA degradation

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039552.4 → NP_001034641.2  ER membrane associated RNA degradation isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC182749
    Consensus CDS
    CCDS37451.1
    UniProtKB/TrEMBL
    B9EKF9, E9Q048
    Related
    ENSMUSP00000095005.4, ENSMUST00000097393.11
    Conserved Domains (1) summary
    pfam13910
    Location:133 → 214
    DUF4209; Domain of unknown function (DUF4209)

  2. NM_001360400.2 → NP_001347329.1  ER membrane associated RNA degradation isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC182749
    Conserved Domains (1) summary
    pfam13910
    Location:7 → 88
    DUF4209; Domain of unknown function (DUF4209)

  3. NM_001360401.2 → NP_001347330.1  ER membrane associated RNA degradation isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC182749

  4. NM_001360402.2 → NP_001347331.1  ER membrane associated RNA degradation isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC182749
    Conserved Domains (1) summary
    pfam13910
    Location:7 → 88
    DUF4209; Domain of unknown function (DUF4209)

  5. NM_001405474.2 → NP_001392403.1  ER membrane associated RNA degradation isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC182749
    UniProtKB/TrEMBL
    B9EKF9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    15261825..15310307
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036160659.1 → XP_036016552.1  ER membrane associated RNA degradation isoform X10

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:133 → 214
    DUF4209; Domain of unknown function (DUF4209)

  2. XM_036160660.1 → XP_036016553.1  ER membrane associated RNA degradation isoform X13

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:133 → 214
    DUF4209; Domain of unknown function (DUF4209)

  3. XM_036160662.1 → XP_036016555.1  ER membrane associated RNA degradation isoform X17

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:133 → 214
    DUF4209; Domain of unknown function (DUF4209)

  4. XM_030249856.2 → XP_030105716.1  ER membrane associated RNA degradation isoform X20

    Conserved Domains (1) summary
    pfam13910
    Location:7 → 88
    DUF4209; Domain of unknown function (DUF4209)

  5. XM_036160664.1 → XP_036016557.1  ER membrane associated RNA degradation isoform X21

    Conserved Domains (1) summary
    pfam13910
    Location:7 → 88
    DUF4209; Domain of unknown function (DUF4209)

  6. XM_036160665.1 → XP_036016558.1  ER membrane associated RNA degradation isoform X23

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  7. XM_036160666.1 → XP_036016559.1  ER membrane associated RNA degradation isoform X23

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  8. XM_030249854.1 → XP_030105714.1  ER membrane associated RNA degradation isoform X19

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  9. XM_006524461.2 → XP_006524524.1  ER membrane associated RNA degradation isoform X4

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:125 → 206
    DUF4209; Domain of unknown function (DUF4209)

  10. XM_030249851.1 → XP_030105711.1  ER membrane associated RNA degradation isoform X12

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:125 → 206
    DUF4209; Domain of unknown function (DUF4209)

  11. XM_030249852.1 → XP_030105712.1  ER membrane associated RNA degradation isoform X14

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:125 → 206
    DUF4209; Domain of unknown function (DUF4209)

  12. XM_006524460.5 → XP_006524523.1  ER membrane associated RNA degradation isoform X3

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:132 → 213
    DUF4209; Domain of unknown function (DUF4209)

  13. XM_006524463.3 → XP_006524526.1  ER membrane associated RNA degradation isoform X8

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  14. XM_011246509.3 → XP_011244811.1  ER membrane associated RNA degradation isoform X5

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  15. XM_036160661.1 → XP_036016554.1  ER membrane associated RNA degradation isoform X15

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  16. XM_011246510.3 → XP_011244812.1  ER membrane associated RNA degradation isoform X6

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  17. XM_006524462.4 → XP_006524525.1  ER membrane associated RNA degradation isoform X7

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  18. XM_006524458.3 → XP_006524521.1  ER membrane associated RNA degradation isoform X1

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  19. XM_006524464.3 → XP_006524527.1  ER membrane associated RNA degradation isoform X9

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  20. XM_006524465.3 → XP_006524528.1  ER membrane associated RNA degradation isoform X11

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  21. XM_006524466.4 → XP_006524529.1  ER membrane associated RNA degradation isoform X16

    UniProtKB/TrEMBL
    B9EKF9
    Conserved Domains (1) summary
    pfam13910
    Location:157 → 238
    DUF4209; Domain of unknown function (DUF4209)

  22. XM_030249855.2 → XP_030105715.1  ER membrane associated RNA degradation isoform X19

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  23. XM_030249858.2 → XP_030105718.1  ER membrane associated RNA degradation isoform X23

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  24. XM_030249857.1 → XP_030105717.1  ER membrane associated RNA degradation isoform X22

    Conserved Domains (1) summary
    pfam13910
    Location:62 → 151
    DUF4209; Domain of unknown function (DUF4209)

  25. XM_030249853.2 → XP_030105713.1  ER membrane associated RNA degradation isoform X18

    Conserved Domains (1) summary
    pfam13910
    Location:1 → 45
    DUF4209; Domain of unknown function (DUF4209)

  26. XM_036160663.1 → XP_036016556.1  ER membrane associated RNA degradation isoform X18

    Conserved Domains (1) summary
    pfam13910
    Location:1 → 45
    DUF4209; Domain of unknown function (DUF4209)

RNA

  1. XR_004939545.1 RNA Sequence

  2. XR_385340.3 RNA Sequence

  3. XR_876519.3 RNA Sequence

  4. XR_876517.3 RNA Sequence

  5. XR_385342.3 RNA Sequence

  6. XR_004939544.1 RNA Sequence

  7. XR_003952143.2 RNA Sequence

  8. XR_004939543.1 RNA Sequence

  9. XR_003952144.2 RNA Sequence

  10. XR_003952142.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001034891.3: Suppressed sequence

    Description
    NM_001034891.3: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.

  2. NM_183133.1: Suppressed sequence

    Description
    NM_183133.1: This RefSeq was temporarily suppressed because its source sequence, AK019108.1, does not represent an intron/exon definition that is supported by other available sequence data.

  3. NM_198646.1: Suppressed sequence

    Description
    NM_198646.1: This RefSeq was permanently suppressed because it is a nonsense-mediated decay (NMD) candidate.
Nucleotide Protein Strain
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