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hsd17b12.S hydroxysteroid (17-beta) dehydrogenase 12 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 379747, updated on 11-Apr-2024

Summary

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Official Symbol
hsd17b12.S
Official Full Name
hydroxysteroid (17-beta) dehydrogenase 12 S homeolog
Primary source
Xenbase:XB-GENE-945234
Locus tag
XELAEV_18024537mg
See related
EnsemblRapid:ENSXLAG00005023673
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
kar; sdr12c1; hsd17b12; let-767co; hsd17b12-a; hsd17b12-b
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Genomic context

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Location:
chromosome: 4S
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (16654508..16718563, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (16062201..16126270, complement)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein C11orf96 homolog Neighboring gene uncharacterized protein C11orf96 homolog Neighboring gene uncharacterized LOC121393188 Neighboring gene uncharacterized LOC121393189

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC52629

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables estradiol 17-beta-dehydrogenase [NAD(P)] activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables very-long-chain 3-oxoacyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within estrogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within steroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
very-long-chain 3-oxoacyl-CoA reductase-B
Names
17-beta-HSD 12-B
17-beta-hydroxysteroid dehydrogenase 12-B
3-ketoacyl-CoA reductase
estradiol 17-beta-dehydrogenase 12-B
NP_001080055.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001086586.2 → NP_001080055.1  very-long-chain 3-oxoacyl-CoA reductase-B

    See identical proteins and their annotated locations for NP_001080055.1

    Status: PROVISIONAL

    Source sequence(s)
    BC041194
    UniProtKB/Swiss-Prot
    Q8AVY8
    UniProtKB/TrEMBL
    A0A974CXW3
    Related
    ENSXLAP00005070083.1, ENSXLAT00005071618.1
    Conserved Domains (2) summary
    cd05356
    Location:54 → 294
    17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
    pfam00106
    Location:55 → 246
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    16654508..16718563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8AVY8.1 GenPept UniProtKB/Swiss-Prot:Q8AVY8

Gene LinkOut

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