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CG12782 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37685, updated on 10-May-2024

Summary

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Official Symbol
CG12782provided by FlyBase
Primary source
FLYBASE:FBgn0034838
Locus tag
Dmel_CG12782
See related
AllianceGenome:FB:FBgn0034838
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG12782
Summary
Predicted to enable RNA binding activity and ubiquitin binding activity. Predicted to be involved in RNA export from nucleus and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Predicted to be part of nuclear pore. Orthologous to human RAE1 (ribonucleic acid export 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See CG12782 in Genome Data Viewer
Location:
59D4-59D4; 2-102 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23264269..23265543, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19151792..19153066, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L22-like Neighboring gene yippee interacting protein 3 Neighboring gene uncharacterized protein Neighboring gene orientation disruptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila rae1 is required for male meiosis and spermatogenesis. Volpi S, et al. J Cell Sci, 2013 Aug 15. PMID 23788425
  2. Gene expression profiling of brakeless mutant Drosophila embryos. Crona F, et al. Data Brief, 2015 Dec. PMID 26509186, Free PMC Article
  3. Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits. Durham MF, et al. Nat Commun, 2014 Jul 8. PMID 25000897
  4. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
  5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in RNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG12782-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    23264269..23265543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137928.3 → NP_611772.2  uncharacterized protein Dmel_CG12782 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_611772.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T4A6, Q9W1T0
    Related
    FBpp0071957
    Conserved Domains (3) summary
    COG2319
    Location:19 → 303
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:26 → 64
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:25 → 303
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T4A6 Q8T4A6
Q9W1T0 Q9W1T0

Gene LinkOut

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