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CDC46 MCM DNA helicase complex subunit [ Candida albicans SC5314 ]

Gene ID: 3646912, updated on 30-Nov-2023

Summary

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Gene symbol
CDC46
Gene description
MCM DNA helicase complex subunit
Locus tag
CAALFM_C206250CA
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Candida albicans SC5314 (strain: SC5314, nat-host: Homo sapiens, culture-collection: ATCC:MYA-2876)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida
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Genomic context

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See CDC46 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_032090.1 (1272572..1274758, complement)

Chromosome 2 - NC_032090.1Genomic Context describing neighboring genes Neighboring gene cleavage polyadenylation factor subunit Neighboring gene mRNA splicing protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032090.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. O'Meara TR, et al. PLoS Biol, 2019 Jul. PMID 31283755, Free PMC Article
  2. Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Muzzey D, et al. Genome Biol, 2013. PMID 24025428, Free PMC Article
  3. Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. van het Hoog M, et al. Genome Biol, 2007. PMID 17419877, Free PMC Article
  4. The diploid genome sequence of Candida albicans. Jones T, et al. Proc Natl Acad Sci U S A, 2004 May 11. PMID 15123810, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via break-induced replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MCM complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MCM DNA helicase complex subunit
XP_711479.1
  • Putative hexameric MCM complex subunit; predicted role in control of cell division; periodic mRNA expression. peak at cell-cycle M/G1 phase; regulated by tyrosol, cell density, Plc1; repressed by alpha pheromone in SpiderM medium

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_032090.1 Reference assembly

    Range
    1272572..1274758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_706387.2 → XP_711479.1  MCM DNA helicase complex subunit [Candida albicans SC5314]

    See identical proteins and their annotated locations for XP_711479.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H6BT54, C4YIU0, Q59P49
    Conserved Domains (2) summary
    smart00350
    Location:127 → 645
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:29 → 121
    MCM_N; MCM N-terminal domain
Nucleotide Protein
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