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Abhd11 abhydrolase domain containing 11 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360831, updated on 6-Jun-2024

Summary

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Official Symbol
Abhd11provided by RGD
Official Full Name
abhydrolase domain containing 11provided by RGD
Primary source
RGD:1304681
See related
Ensembl:ENSRNOG00000018910 AllianceGenome:RGD:1304681
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Wbscr21; Abhd11l1
Summary
Predicted to enable hydrolase activity. Predicted to be active in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 68.8), Heart (RPKM 56.3) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Abhd11 in Genome Data Viewer
Location:
12q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (27318739..27322016, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (21682206..21685331, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (24722277..24725760, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene syntaxin 1A Neighboring gene ABHD11 antisense RNA 1 (tail to tail) Neighboring gene claudin 3 Neighboring gene ribosomal protein S13, pseudogene 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables carboxylic ester hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cellular lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of oxoglutarate dehydrogenase complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
sn-1-specific diacylglycerol lipase ABHD11
Names
Williams Beuren syndrome chromosome region 21
abhydrolase domain containing 11-like 1
alpha/beta hydrolase domain-containing protein 11
NP_001258109.1
XP_063127622.1
XP_063127623.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271180.1 → NP_001258109.1  sn-1-specific diacylglycerol lipase ABHD11

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/TrEMBL
    A6J0G1, D3ZXK4
    Related
    ENSRNOP00000025560.4, ENSRNOT00000025560.7
    Conserved Domains (2) summary
    PRK10673
    Location:61 → 307
    PRK10673; acyl-CoA esterase; Provisional
    pfam12695
    Location:60 → 195
    Abhydrolase_5; Alpha/beta hydrolase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    27318739..27322016 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063271552.1 → XP_063127622.1  sn-1-specific diacylglycerol lipase ABHD11 isoform X1

    UniProtKB/TrEMBL
    A6J0G1

  2. XM_063271553.1 → XP_063127623.1  sn-1-specific diacylglycerol lipase ABHD11 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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