U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG14763 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35757, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CG14763provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033243
Locus tag
Dmel_CG14763
See related
AllianceGenome:FB:FBgn0033243
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG14763
Summary
Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNLT2 (dynein light chain Tctex-type 2) and DYNLT2B (dynein light chain Tctex-type 2B). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
43F9-43F9; 2-57 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7966029..7968024, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3853534..3855529, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Septin 5 Neighboring gene spenito Neighboring gene uncharacterized protein Neighboring gene COP9 signalosome subunit 4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The Krüppel-Like Factor Dar1 Determines Multipolar Neuron Morphology. Wang X, et al. J Neurosci, 2015 Oct 21. PMID 26490864, Free PMC Article
  2. Flying through the drosophila cytoskeletal genome. Goldstein LS, et al. J Cell Biol, 2000 Jul 24. PMID 10908588, Free PMC Article
  3. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
  4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
  5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables dynein intermediate chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytoplasmic dynein complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG14763-PA
CG14763-PB
CG14763-PC
CG14763-PD

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7966029..7968024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299247.1 → NP_001286176.1  uncharacterized protein Dmel_CG14763, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286176.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K035
    Conserved Domains (1) summary
    cl41776
    Location:86 → 186
    DLC-like_SF; dynein light chain (DLC)-like domain superfamily

  2. NM_001299246.1 → NP_001286175.1  uncharacterized protein Dmel_CG14763, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286175.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K035
    Conserved Domains (1) summary
    cl41776
    Location:86 → 186
    DLC-like_SF; dynein light chain (DLC)-like domain superfamily

  3. NM_136496.3 → NP_610340.1  uncharacterized protein Dmel_CG14763, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610340.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K035
    Related
    FBpp0087951
    Conserved Domains (1) summary
    cl41776
    Location:86 → 186
    DLC-like_SF; dynein light chain (DLC)-like domain superfamily

  4. NM_001382031.1 → NP_001369065.1  uncharacterized protein Dmel_CG14763, isoform D [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A6M3QGX6
    Conserved Domains (1) summary
    cd21451
    Location:68 → 168
    DLC-like_TCTEX1D; dynein light chain (DLC)-like domain found in the Tctex1 domain-containing protein (TCTEX1D) family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A6M3QGX6 A0A6M3QGX6
Q7K035 Q7K035

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools