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eIF3f2 eukaryotic translation initiation factor 3 subunit f2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35547, updated on 10-May-2024

Summary

Official Symbol
eIF3f2provided by FlyBase
Official Full Name
eukaryotic translation initiation factor 3 subunit f2provided by FlyBase
Primary source
FLYBASE:FBgn0033069
Locus tag
Dmel_CG8335
See related
AllianceGenome:FB:FBgn0033069
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8335; Dmel\CG8335; eIF3-S5; eIF3f
Summary
Predicted to enable deubiquitinase activity and translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in protein deubiquitination and translational initiation. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human EIF3F (eukaryotic translation initiation factor 3 subunit F). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See eIF3f2 in Genome Data Viewer
Location:
42A13-42A13; 2-55 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6200853..6201956)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2088358..2089461)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Patched-related Neighboring gene transfer RNA:Asparagine-GTT 1-8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metal-dependent deubiquitinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
enables translation initiation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables translation initiation factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables translation initiation factor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein deubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in translational initiation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
part_of eukaryotic translation initiation factor 3 complex IEA
Inferred from Electronic Annotation
more info
 
part_of eukaryotic translation initiation factor 3 complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of eukaryotic translation initiation factor 3 complex, eIF3m IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
eukaryotic translation initiation factor 3 subunit f2
Names
CG8335-PA
eIF3f2-PA
NP_610210.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    6200853..6201956
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136366.3NP_610210.2  eukaryotic translation initiation factor 3 subunit f2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610210.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1Z6K7
    UniProtKB/TrEMBL
    C6SUU7, H1UU98
    Related
    FBpp0085334
    Conserved Domains (1) summary
    cd08064
    Location:12280
    MPN_eIF3f; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in eIF3f