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TpnC41C Troponin C at 41C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35473, updated on 4-Apr-2024

Summary

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Official Symbol
TpnC41Cprovided by FlyBase
Official Full Name
Troponin C at 41Cprovided by FlyBase
Primary source
FLYBASE:FBgn0013348
Locus tag
Dmel_CG2981
See related
AllianceGenome:FB:FBgn0013348
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2981; Dmel\CG2981; DmTnC1; DmTpnC41C; DmTpnCIIIa; TnC; Tnc1; TnC1; TnC41C; TNC41C; TPNC; TpnC IIIa; TpnC4; TpnC41; TPnC41C; TpnCIIIa
Summary
Predicted to enable calcium ion binding activity and enzyme regulator activity. Is expressed in adult heart; indirect flight muscle cell; leg; muscle cell of mesothoracic extracoxal depressor muscle 66; and organism. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
41D1-41D1; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5065237..5070210, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (952742..957715, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 41a Neighboring gene long non-coding RNA:CR44105 Neighboring gene pseudo Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional redundancy and nonredundancy between two Troponin C isoforms in Drosophila adult muscles. Chechenova MB, et al. Mol Biol Cell, 2017 Mar 15. PMID 28077621, Free PMC Article
  2. Neural control and precision of flight muscle activation in Drosophila. Lehmann FO, et al. J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 2017 Jan. PMID 27942807, Free PMC Article
  3. Expression of the Troponin C at 41C Gene in Adult Drosophila Tubular Muscles Depends upon Both Positive and Negative Regulatory Inputs. Chechenova MB, et al. PLoS One, 2015. PMID 26641463, Free PMC Article
  4. The roles of troponin C isoforms in the mechanical function of Drosophila indirect flight muscle. Eldred CC, et al. J Muscle Res Cell Motil, 2014 Aug. PMID 25134799, Free PMC Article
  5. Drosophila melanogaster genes encoding three troponin-C isoforms and a calmodulin-related protein. Fyrberg C, et al. Biochem Genet, 1994 Apr. PMID 7980384

See all (71) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TnC1 was found to be not essential for the mechanical function of indirect flight muscle.
    Title: The roles of troponin C isoforms in the mechanical function of Drosophila indirect flight muscle.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables enzyme regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
troponin C at 41C
Names
CG2981-PA
CG2981-PB
TpnC41C-PA
TpnC41C-PB
TroponinC at 41C
troponin C
troponin-C

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5065237..5070210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001259210.1 → NP_001246139.1  troponin C at 41C, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246139.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P47947, Q9V9E1
    UniProtKB/TrEMBL
    A0A0B4K6P6
    Conserved Domains (1) summary
    PTZ00184
    Location:1 → 150
    PTZ00184; calmodulin; Provisional

  2. NM_078895.4 → NP_523619.2  troponin C at 41C, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523619.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P47947, Q9V9E1
    UniProtKB/TrEMBL
    A0A0B4K6P6
    Related
    FBpp0085438
    Conserved Domains (1) summary
    PTZ00184
    Location:1 → 150
    PTZ00184; calmodulin; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4K6P6 A0A0B4K6P6
P47947.2 P47947

Gene LinkOut

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