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AFUA_3G10660 hydroxymethylglutaryl-CoA synthase Erg13, putative [ Aspergillus fumigatus Af293 ]

Gene ID: 3512339, updated on 3-Apr-2024

Summary

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Gene symbol
AFUA_3G10660
Gene description
hydroxymethylglutaryl-CoA synthase Erg13, putative
Locus tag
AFUA_3G10660
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Aspergillus fumigatus Af293 (strain: Af293)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Fumigati
Old locus tag
Afu3g10660
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Genomic context

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See AFUA_3G10660 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_007196.1 (2760689..2762268)

Chromosome 3 - NC_007196.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene glutamate carboxypeptidase Tre2, putative Neighboring gene hypothetical protein Neighboring gene FAD binding domain protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007196.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nierman WC, et al. Nature, 2005 Dec 22. PMID 16372009

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ergosterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase Erg13, putative
XP_754553.1
  • encoded by transcript AFUA_3G10660A
    similar to 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis; Erg13p (GI:6323509) [Saccharomyces cerevisiae] similar to Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) (HMG-CoA synthase)(3-hydroxy-3-methylglutaryl coenzyme A synthase). (Swiss-Prot:P54874) [Schizosaccharomyces pombe] PMID: 8750242

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007196.1 Reference assembly

    Range
    2760689..2762268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_749460.1 → XP_754553.1  hydroxymethylglutaryl-CoA synthase Erg13, putative [Aspergillus fumigatus Af293]

    See identical proteins and their annotated locations for XP_754553.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q4WXT8
    UniProtKB/TrEMBL
    A0A9P8ST11, B0XXT5
    Conserved Domains (1) summary
    TIGR01833
    Location:4 → 459
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
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