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CG5790 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35095, updated on 26-Apr-2024

Summary

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Official Symbol
CG5790provided by FlyBase
Primary source
FLYBASE:FBgn0032677
Locus tag
Dmel_CG5790
See related
AllianceGenome:FB:FBgn0032677
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5790
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in double-strand break repair via break-induced replication and peptidyl-serine phosphorylation. Part of Dbf4-dependent protein kinase complex. Orthologous to human CDC7 (cell division cycle 7). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
36F2-36F2; 2-53 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18294840..18297347)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18294840..18297347)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43358 Neighboring gene Seminal fluid protein 36F Neighboring gene long non-coding RNA:CR43353 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of a Drosophila ortholog of the Cdc7 kinase: a role for Cdc7 in endoreplication independent of Chiffon. Stephenson R, et al. J Biol Chem, 2015 Jan 16. PMID 25451925, Free PMC Article
  2. Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila. Reid DW, et al. Front Cell Infect Microbiol, 2012. PMID 22919616, Free PMC Article
  3. Drosophila muscleblind is involved in troponin T alternative splicing and apoptosis. Vicente-Crespo M, et al. PLoS One, 2008 Feb 20. PMID 18286170, Free PMC Article
  4. Sex-specific role of Drosophila melanogaster HP1 in regulating chromatin structure and gene transcription. Liu LP, et al. Nat Genet, 2005 Dec. PMID 16258543
  5. Spatial and temporal control of gene expression in Drosophila using the inducible GeneSwitch GAL4 system. I. Screen for larval nervous system drivers. Nicholson L, et al. Genetics, 2008 Jan. PMID 18202369, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic DNA damage checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Dbf4-dependent protein kinase complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CDC 7-related
CG5790-PA
CG5790-PB
NP_001286037.1
NP_609876.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18294840..18297347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299108.1 → NP_001286037.1  uncharacterized protein Dmel_CG5790, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286037.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJ90
    Conserved Domains (3) summary
    smart00220
    Location:145 → 597
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14019
    Location:143 → 597
    STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
    cl21453
    Location:427 → 597
    PKc_like; Protein Kinases, catalytic domain

  2. NM_136032.4 → NP_609876.2  uncharacterized protein Dmel_CG5790, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609876.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJ90
    Related
    FBpp0080603
    Conserved Domains (3) summary
    smart00220
    Location:145 → 597
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14019
    Location:143 → 597
    STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
    cl21453
    Location:427 → 597
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8T0Q5 Q8T0Q5
Q9VJ90 Q9VJ90

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