U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pes peste [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34087, updated on 10-May-2024

Summary

Go to the top of the page Help
Official Symbol
pesprovided by FlyBase
Official Full Name
pesteprovided by FlyBase
Primary source
FLYBASE:FBgn0031969
Locus tag
Dmel_CG7228
See related
AllianceGenome:FB:FBgn0031969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG7228; Dmel\CG7228; Pes; Peste
Summary
Predicted to enable scavenger receptor activity. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval anterior spiracle; embryonic/larval digestive system; excretory system; gonad; and ring gland. Orthologous to human SCARB1 (scavenger receptor class B member 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See pes in Genome Data Viewer
Location:
28D3-28D3; 2-29 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7986786..7994184, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7986786..7994184, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Serpin 28Db Neighboring gene Sno oncogene Neighboring gene antisense RNA:CR44996 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Starvation-upregulated protein Neighboring gene WW domain containing oxidoreductase

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Population genetic analysis of autophagy and phagocytosis genes in Drosophila melanogaster and D. simulans. Im JH, et al. PLoS One, 2018. PMID 30281656, Free PMC Article
  2. Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Philips JA, et al. Science, 2005 Aug 19. PMID 16020694
  3. The insect SNMP gene family. Vogt RG, et al. Insect Biochem Mol Biol, 2009 Jul. PMID 19364529
  4. Applications of high-throughput RNA interference screens to problems in cell and developmental biology. Perrimon N, et al. Genetics, 2007 Jan. PMID 17244760, Free PMC Article
  5. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Agaisse H, et al. Science, 2005 Aug 19. PMID 16020693

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results show highly regulated expression patterns, with three genes crq, pes and Snmp being upregulated in steroidogenic tissues at the onset of pupariation when steroidogenesis is crucial
    Title: Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster.
  2. CG7228 (Peste) is a CD36 family member required for uptake of mycobacteria
    Title: Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables scavenger receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
peste
Names
CG7228-PC
CG7228-PD
CG7228-PE
CG7228-PF
CG7228-PG
CG7228-PH
pes-PC
pes-PD
pes-PE
pes-PF
pes-PG
pes-PH

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    7986786..7994184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164777.3 → NP_723328.2  peste, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723328.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7Z031, Q8SXU4, Q9VLU8
    Conserved Domains (1) summary
    pfam01130
    Location:14 → 463
    CD36; CD36 family

  2. NM_001144336.3 → NP_001137808.1  peste, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001137808.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7Z031, Q8SXU4, Q9VLU8
    Conserved Domains (1) summary
    pfam01130
    Location:14 → 463
    CD36; CD36 family

  3. NM_001298802.1 → NP_001285731.1  peste, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285731.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7Z031, Q8SXU4, Q9VLU8
    Conserved Domains (1) summary
    pfam01130
    Location:14 → 463
    CD36; CD36 family

  4. NM_001298803.1 → NP_001285732.1  peste, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285732.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7Z031, Q8SXU4, Q9VLU8
    Conserved Domains (1) summary
    pfam01130
    Location:14 → 463
    CD36; CD36 family

  5. NM_135324.3 → NP_609168.2  peste, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609168.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B7Z031, Q8SXU4, Q9VLU8
    Conserved Domains (1) summary
    pfam01130
    Location:14 → 463
    CD36; CD36 family

  6. NM_001273290.1 → NP_001260219.1  peste, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260219.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCW1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B7Z031.1 B7Z031
M9PCW1 M9PCW1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools
Miscellaneous