U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

stnA stoned A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3355164, updated on 10-May-2024

Summary

Go to the top of the page Help
Official Symbol
stnAprovided by FlyBase
Official Full Name
stoned Aprovided by FlyBase
Primary source
FLYBASE:FBgn0016976
Locus tag
Dmel_CG12500
See related
AllianceGenome:FB:FBgn0016976
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
20; 31; 32; 8P1; CG12500; CG40306; Dmel\CG12500; l(1)13-20; l(1)20Bc; l(1)X-3; l8P1; lR9-10; ORF1; sesC; stn; stn-A; StnA; STNA; x-3; X-3; X-43; X3
Summary
Involved in synaptic vesicle endocytosis and synaptic vesicle transport. Located in endocytic vesicle and synaptic vesicle. Is expressed in adult abdomen; adult head; and adult thorax. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See stnA in Genome Data Viewer
Location:
20F3-20F3; 1-66 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (22980722..23004648, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (22382558..22406484, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene stoned B Neighboring gene antisense RNA:CR45009 Neighboring gene long non-coding RNA:CR45010 Neighboring gene alpha1,3-fucosyltransferase C

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. An altered electroretinogram transient associated with an unusual jump response in a mutant of Drosophila. Kelly LE. Cell Mol Neurobiol, 1983 Jun. PMID 6418384
  2. Ca2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1. Soekmadji C, et al. PLoS One, 2012. PMID 22701718, Free PMC Article
  3. Effective translation of the second cistron in two Drosophila dicistronic transcripts is determined by the absence of in-frame AUG codons in the first cistron. Wall AA, et al. J Biol Chem, 2005 Jul 29. PMID 15951443
  4. The regulation of phosphorylation of a specific protein in synaptosomal fractions from Drosophila heads: the effects of light and two visual mutants. Kelly LE. Cell Mol Neurobiol, 1983 Jun. PMID 6317178
  5. A product of the Drosophila stoned locus regulates neurotransmitter release. Stimson DT, et al. J Neurosci, 1998 Dec 1. PMID 9822725, Free PMC Article

See all (69) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Stoned proteins may regulate sustainable neurotransmission in vivo by binding to Ca(2+)-bound Synaptotagmin-1 associated synaptic vesicles.
    Title: Ca2+ regulates the Drosophila Stoned-A and Stoned-B proteins interaction with the C2B domain of Synaptotagmin-1.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

mobile_element

  • Loc: c22983800-22983677 mobile_element_type = transposon:INE-1{}3879
  • Loc: c22984008-22983905 mobile_element_type = transposon:INE-1{}3880
  • Loc: c22994189-22994067 mobile_element_type = transposon:INE-1{}3883

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in synaptic vesicle endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in synaptic vesicle transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in endocytic vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in synaptic vesicle IGI
Inferred from Genetic Interaction
more info
 PubMed 
located_in synaptic vesicle IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
stoned A
Names
CG12500-PC
CG12500-PD
CG12500-PE
CG12500-PF
section 20
section 31
section 32
stnA-PC
stnA-PD
stnA-PE
stnA-PF
stoned
stonedA
stress-sensitive-C

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    22980722..23004648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001042851.3 → NP_001036316.1  stoned A, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036316.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24211, Q7PLF2, Q9W5M8
    UniProtKB/TrEMBL
    A4V4W0

  2. NM_001298609.1 → NP_001285538.1  stoned A, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285538.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24211, Q7PLF2, Q9W5M8
    UniProtKB/TrEMBL
    A4V4W0

  3. NM_001042852.3 → NP_001036317.1  stoned A, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036317.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24211, Q7PLF2, Q9W5M8
    UniProtKB/TrEMBL
    A4V4W0

  4. NM_001298608.1 → NP_001285537.1  stoned A, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285537.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24211, Q7PLF2, Q9W5M8
    UniProtKB/TrEMBL
    A4V4W0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4V4W0 A4V4W0
Q24211.3 Q24211

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous