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CG41128 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3355108, updated on 18-Sep-2024

Summary

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Official Symbol
CG41128provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0069923
Locus tag
Dmel_CG41128
See related
AllianceGenome:FB:FBgn0069923
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:RH61753; Dmel\CG41128; Minos1b; RH61753p
Summary
Predicted to be part of MICOS complex. Predicted to be active in mitochondrion. Is expressed in adult head; adult heart; and organism. Orthologous to human MICOS10 (mitochondrial contact site and cristae organizing system subunit 10). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
81F5-81F5; 3-47.1 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (3750363..3752353)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3RHet NW_001848858.1 (1806528..1808518, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46141 Neighboring gene Translocase of the inner mitochondrial membrane 17b Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The RNA-Binding Protein Rasputin/G3BP Enhances the Stability and Translation of Its Target mRNAs. Laver JD, et al. Cell Rep, 2020 Mar 10. PMID 32160542
  2. Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD. Li S, et al. Cell Rep, 2020 Aug 4. PMID 32755582, Free PMC Article
  3. The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. Landskron L, et al. Elife, 2018 Mar 27. PMID 29580384, Free PMC Article
  4. The Organization of Pericentromeric Heterochromatin in Polytene Chromosome 3 of the Drosophilamelanogaster Line with the Rif1(1); SuUR(ES) Su(var)3-9(06) Mutations Suppressing Underreplication. Zykova T, et al. Cells, 2021 Oct 20. PMID 34831030, Free PMC Article
  5. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

  • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in cristae formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in inner mitochondrial membrane organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of MICOS complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of MICOS complex IEA
Inferred from Electronic Annotation
more info
  
part_of MICOS complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG41128-PB
mitochondrial INner membrane organizing system 1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    3750363..3752353
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001015402.3 → NP_001015402.3  uncharacterized protein Dmel_CG41128 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001015402.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5LJS0, Q8SY69
    Conserved Domains (1) summary
    pfam04418
    Location:2 → 69
    DUF543; Domain of unknown function (DUF543)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SY69 Q8SY69

Gene LinkOut

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