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CG9663 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 33541, updated on 18-Sep-2024

Summary

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Official Symbol
CG9663provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0031516
Locus tag
Dmel_CG9663
See related
AllianceGenome:FB:FBgn0031516
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
DmCG9663; Dmel\CG9663
Summary
Predicted to enable ATP binding activity; ATP hydrolysis activity; and ATPase-coupled transmembrane transporter activity. Predicted to be active in plasma membrane. Is expressed in several structures, including embryonic precursor of adult hindgut; embryonic/larval fat body; embryonic/larval muscle system; extended germ band embryo; and visceral muscle primordium. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1) and ABCG4 (ATP binding cassette subfamily G member 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
23E1-23E3; 2-9 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3294926..3303130, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3294926..3303130, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44485 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Fidgetin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans. Zhang D, et al. Nat Ecol Evol, 2022 Mar. PMID 34969986
  2. Mutants of the white ABCG Transporter in Drosophila melanogaster Have Deficient Olfactory Learning and Cholesterol Homeostasis. Myers JL, et al. Int J Mol Sci, 2021 Nov 30. PMID 34884779, Free PMC Article
  3. Characterization of a novel pesticide transporter and P-glycoprotein orthologues in Drosophila melanogaster. Denecke S, et al. Proc Biol Sci, 2022 May 25. PMID 35582794, Free PMC Article
  4. TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels. Ren Q, et al. Nucleic Acids Res, 2007 Jan. PMID 17135193, Free PMC Article
  5. ATP-Binding Cassette (ABC) Transporter Genes Involved in Pyrethroid Resistance in the Malaria Vector Anopheles sinensis: Genome-Wide Identification, Characteristics, Phylogenetics, and Expression Profile. He Q, et al. Int J Mol Sci, 2019 Mar 20. PMID 30897799, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG9663-PA
NP_608760.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    3294926..3303130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_134916.4 → NP_608760.2  uncharacterized protein Dmel_CG9663 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_608760.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MRL3, Q9VQN5
    Related
    FBpp0077291
    Conserved Domains (3) summary
    cd03213
    Location:145 → 370
    ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily
    TIGR00955
    Location:149 → 808
    3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
    pfam01061
    Location:540 → 743
    ABC2_membrane; ABC-2 type transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MRL3 Q8MRL3

Gene LinkOut

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