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Or10a Odorant receptor 10a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32086, updated on 4-Apr-2024

Summary

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Official Symbol
Or10aprovided by FlyBase
Official Full Name
Odorant receptor 10aprovided by FlyBase
Primary source
FLYBASE:FBgn0030298
Locus tag
Dmel_CG17867
See related
AllianceGenome:FB:FBgn0030298
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
10a; 10B.1; CG17867; Dmel\CG17867; DOR92; Gr10a; OR10a
Summary
Enables olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Is integral component of membrane. Is expressed in adult olfactory receptor neuron Or10a; antennal basiconic sensillum ab1; and antennal lobe glomerulus DL1. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
10B10-10B10; 1-34 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11413467..11417422, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11309613..11311455, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor 10b Neighboring gene Gustatory receptor 10a Neighboring gene Glutamine synthetase 2 Neighboring gene Ecotropic viral integration site 5 Neighboring gene Sphingosine kinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multimodal chemosensory integration through the maxillary palp in Drosophila. Shiraiwa T. PLoS One, 2008 May 14. PMID 18478104, Free PMC Article
  2. An ultrasensitive electrochemical impedance-based biosensor using insect odorant receptors to detect odorants. Khadka R, et al. Biosens Bioelectron, 2019 Feb 1. PMID 30415156
  3. The molecular and cellular basis of olfactory response to tsetse fly attractants. Chahda JS, et al. PLoS Genet, 2019 Mar. PMID 30875383, Free PMC Article
  4. Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors. Murugathas T, et al. ACS Appl Mater Interfaces, 2019 Mar 6. PMID 30740970
  5. The bacterial metabolite 2-aminoacetophenone promotes association of pathogenic bacteria with flies. Kapsetaki SE, et al. Nat Commun, 2014 Jul 21. PMID 25043228

See all (78) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables olfactory receptor activity HDA PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell HDA PubMed 
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
odorant receptor 10a
Names
CG17867-PB
Or10a-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11413467..11417422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078567.5 → NP_511122.1  odorant receptor 10a [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511122.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VYZ1
    UniProtKB/TrEMBL
    E2E510, E2E519, E2E522, E2E528, E2E536, E2E543, E2E547, E2E569, E2E578, E2E5A1, E2E5B5, E2E5D4, E2E5H6
    Related
    FBpp0312370
    Conserved Domains (1) summary
    pfam02949
    Location:70 → 396
    7tm_6; 7tm Odorant receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VYZ1.1 Q9VYZ1

Gene LinkOut

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