ATPsyndelta ATP synthase, delta subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ATPsyndeltaprovided by FlyBase
Official Full Name: ATP synthase, delta subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0028342
Locus tag: Dmel_CG2968
See related: AllianceGenome:FB:FBgn0028342
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO03040301.109; anon-WO03040301.110; ATP5D; ATPD; CG2968; Dmel\CG2968; l (1) G0230; l(1)G0230
Summary: Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in ATP synthesis coupled proton transport. Located in mitochondrion. Is expressed in several structures, including adult heart; embryonic/larval midgut; extended germ band embryo; germ layer; and spermatozoon. Used to study inherited metabolic disorder. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency. Orthologous to human ATP5F1D (ATP synthase F1 subunit delta). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (10212970..10217393)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (10107003..10111426)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
enables proton-transporting ATP synthase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info
contributes_to proton-transporting ATP synthase activity, rotational mechanism	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in proton motive force-driven ATP synthesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in proton motive force-driven ATP synthesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial proton-transporting ATP synthase, central stalk	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	HDA more info	PubMed
part_of proton-transporting ATP synthase complex, catalytic core F(1)	IEA Inferred from Electronic Annotation more info

Names: ATP synthase delta chain; ATPsyndelta-PA; ATPsyndelta-PB; ATPsyndelta-PC; CG2968-PA; CG2968-PB; CG2968-PC; F0/F1 ATP synthase delta; lethal (1) G0230

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